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acyl-CoA synthetase medium chain family member 5

Summary

Gene Symbol

ACSM5

Organism

Acinonyx jubatus (cheetah)

External Links

NCBI Gene: 106970531
KEGG Gene ID: aju:106970531
PubChem: 106970531

Annotation

Keyword

Ligase
Lipid metabolism
Nucleotide-binding
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A6I9ZNA4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
fatty acid biosynthetic process	IEA	30032202
acyl-CoA metabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

amide metabolic process [inference]

acyl-CoA metabolic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

sulfur compound metabolic process [inference]

thioester metabolic process [inference]

acyl-CoA metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

thioester metabolic process [inference]

acyl-CoA metabolic process

carbohydrate derivative metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

sulfur compound metabolic process [inference]

thioester metabolic process [inference]

acyl-CoA metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
mitochondrial matrix	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

Displaying **all 2** entries
GO Term	Evidence Code	PMID
fatty-acyl-CoA synthase activity	IEA	30032202
fatty acid ligase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

C-acyltransferase activity [inference]

fatty-acyl-CoA synthase activity

ligase activity [inference]

ligase activity, forming carbon-sulfur bonds [inference]

acid-thiol ligase activity [inference]

fatty acid ligase activity

ATP-dependent activity [inference]

fatty acid ligase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Carnivora

Group Name

acyl-coenzyme A synthetase ACSM5, mitochondrial

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 8** entries
Gene Ontology
CoA-ligase activity
acid-thiol ligase activity
acyl-CoA metabolic process
fatty acid ligase activity
fatty-acyl-CoA synthase activity
ligase activity
lipid metabolic process
nucleotide binding

Displaying **all 5** entries
InterPro
AMP-binding enzyme, C-terminal domain superfamily
AMP-binding enzyme, C-terminal domain
AMP-binding, conserved site
AMP-dependent synthetase/ligase domain
ANL, N-terminal domain

KEGG BRITE Database

Orthology

K01896

Name

medium-chain acyl-CoA synthetase [EC:6.2.1.2]

References

Rhea

ATP + CoA + a medium chain fatty acid

diphosphate + AMP + a medium-chain fatty acyl-CoA

Enzyme

6.2.1.2

PMID

7532480

Ortholog

Displaying entries **1 - 10** of 42 in total

1

2

3

4

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Last updated: December 9, 2024