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DNA polymerase delta 3, accessory subunit

Summary

Gene Symbol

POLD3

Organism

Homo sapiens (human)

External Links

NCBI Gene

10714

PubChem

10714

Alliance of Genome Resources

HGNC:20932

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Cytoplasm
DNA excision
DNA repair
DNA replication
Direct protein sequencing
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q15054	DNA polymerase delta subunit C DNA polymerase delta subunit p66 DNA polymerase delta subunit p68

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
DNA synthesis involved in DNA repair	NAS	7910606
DNA-templated DNA replication	IDA	20334433
DNA strand elongation involved in DNA replication	IBA
nucleotide-excision repair, DNA gap filling	IMP	20227374
nucleotide-excision repair, DNA gap filling	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication [inference]

DNA-templated DNA replication

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

nucleotide-excision repair, DNA gap filling

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication [inference]

DNA-templated DNA replication

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

nucleotide-excision repair, DNA gap filling

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication [inference]

DNA-templated DNA replication

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

nucleotide-excision repair, DNA gap filling

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication [inference]

DNA-templated DNA replication

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

nucleotide-excision repair, DNA gap filling

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication [inference]

DNA-templated DNA replication

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

nucleotide-excision repair, DNA gap filling

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication [inference]

DNA-templated DNA replication

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

nucleotide-excision repair, DNA gap filling

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication [inference]

DNA-templated DNA replication

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

nucleotide-excision repair, DNA gap filling

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication [inference]

DNA-templated DNA replication

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

nucleotide-excision repair, DNA gap filling

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication [inference]

DNA-templated DNA replication

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

nucleotide-excision repair, DNA gap filling

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication [inference]

DNA-templated DNA replication

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

nucleotide-excision repair, DNA gap filling

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-prone translesion synthesis

DNA synthesis involved in UV-damage excision repair

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
nucleoplasm	TAS
nucleoplasm	IDA
cytoplasm	IEA
zeta DNA polymerase complex	IDA	22465957
zeta DNA polymerase complex	IPI	24449906

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

delta DNA polymerase complex

intracellular protein-containing complex [inference]

DNA polymerase complex [inference]

catalytic complex [inference]

transferase complex [inference]

transferase complex, transferring phosphorus-containing groups [inference]

DNA polymerase complex [inference]

cellular anatomical entity [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
DNA-directed DNA polymerase activity	IBA
protein binding	IPI	15576034 16000169 16510448 26496610 28514442 31449058 33961781 38554706
protein-macromolecule adaptor activity	IPI	11595739

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity [inference]

DNA polymerase activity [inference]

DNA-directed DNA polymerase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

DNA polymerase activity [inference]

DNA-directed DNA polymerase activity

binding [inference]

protein binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

DNA polymerase delta subunit 3

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
DNA strand elongation involved in DNA replication
DNA synthesis involved in UV-damage excision repair
nucleotide-excision repair, DNA gap filling

Displaying **all 2** entries
InterPro
DNA polymerase delta subunit 3 superfamily
DNA polymerase delta subunit 3

Ortholog

Displaying entries **1 - 10** of 56 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	10714	Xenbase:XB-GENE-1017222
Mus musculus	67967		MOUSE55288
Rattus norvegicus	293144		RATNO17685
Pan troglodytes	451422		PANTR03821
Canis lupus familiaris	476806		CANLF08271
Danio rerio	692256		DANRE21232
Macaca mulatta	693601		MACMU11464
Equus caballus	100051966		HORSE38068
Ciona intestinalis	100175682		CIOIN14602
Salmo salar	100194857		SALSA120981

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Acknowledgements