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golgi-specific brefeldin A-resistance factor 1

Summary

Gene Symbol

Gbf1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

107338

PubChem

107338

Alliance of Genome Resources

MGI:1861607

Annotation

Keyword

Cytoplasm
Golgi apparatus
Guanine-nucleotide releasing factor
Lipid droplet
Membrane
Phosphoprotein
Protein transport
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6DFZ1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **31 - 35** of 36 in total

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GO Term	Evidence Code	PMID
reactive oxygen species biosynthetic process	ISO
reactive oxygen species biosynthetic process	IEA
protein localization to endoplasmic reticulum tubular network	ISO
protein localization to endoplasmic reticulum tubular network	IEA
regulation of protein localization to cell surface	ISO

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

cell activation involved in immune response

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

myeloid leukocyte migration [inference]

granulocyte migration [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

neutrophil migration [inference]

neutrophil chemotaxis

metabolic process [inference]

biosynthetic process [inference]

reactive oxygen species biosynthetic process

cellular metabolic process [inference]

reactive oxygen species metabolic process [inference]

reactive oxygen species biosynthetic process

cellular process [inference]

cell activation [inference]

cell activation involved in immune response

establishment or maintenance of cell polarity [inference]

establishment of cell polarity [inference]

establishment of monopolar cell polarity

establishment or maintenance of monopolar cell polarity [inference]

establishment of monopolar cell polarity

vesicle-mediated transport

endosomal transport [inference]

retrograde transport, endosome to Golgi

Golgi vesicle transport [inference]

retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

post-Golgi vesicle-mediated transport [inference]

Golgi to endosome transport

cellular metabolic process [inference]

reactive oxygen species metabolic process [inference]

reactive oxygen species biosynthetic process

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

myeloid leukocyte migration [inference]

granulocyte migration [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

neutrophil migration [inference]

neutrophil chemotaxis

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

cellular localization [inference]

intracellular transport [inference]

endosomal transport [inference]

retrograde transport, endosome to Golgi

cytosolic transport [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to Golgi apparatus

protein localization to endoplasmic reticulum [inference]

establishment of protein localization [inference]

protein transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

Golgi organization

Golgi disassembly

vesicle organization [inference]

vesicle coating [inference]

Golgi transport vesicle coating [inference]

COPI coating of Golgi vesicle

endoplasmic reticulum-Golgi intermediate compartment organization

organelle disassembly [inference]

Golgi disassembly

cellular component disassembly [inference]

organelle disassembly [inference]

Golgi disassembly

multicellular organismal process [inference]

cell activation [inference]

cell activation involved in immune response

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

cellular response to virus

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

cellular response to virus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

cellular response to virus

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to Golgi apparatus

protein localization to endoplasmic reticulum [inference]

establishment of protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

vesicle-mediated transport

endosomal transport [inference]

retrograde transport, endosome to Golgi

Golgi vesicle transport [inference]

retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

post-Golgi vesicle-mediated transport [inference]

Golgi to endosome transport

intracellular transport [inference]

endosomal transport [inference]

retrograde transport, endosome to Golgi

cytosolic transport [inference]

organic substance transport [inference]

protein transport

nitrogen compound transport [inference]

protein transport

establishment of protein localization [inference]

protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

endosomal transport [inference]

retrograde transport, endosome to Golgi

cytosolic transport [inference]

cellular localization [inference]

intracellular transport [inference]

endosomal transport [inference]

retrograde transport, endosome to Golgi

cytosolic transport [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to Golgi apparatus

protein localization to endoplasmic reticulum [inference]

establishment of protein localization [inference]

protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of ARF protein signal transduction

regulation of localization [inference]

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to cell surface

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of ARF protein signal transduction

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of ARF protein signal transduction

regulation of cell cycle [inference]

regulation of mitotic cell cycle

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to cell surface

Displaying entries **11 - 15** of 19 in total

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GO Term	Evidence Code	PMID
cis-Golgi network	ISO
cis-Golgi network	IEA
trans-Golgi network	ISO
trans-Golgi network	IEA
lipid droplet	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

cell leading edge

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

lipid droplet

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

intracellular non-membrane-bounded organelle [inference]

lipid droplet

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
guanyl-nucleotide exchange factor activity	IEA
protein binding	IPI	12634853
phosphatidylinositol-3,4,5-trisphosphate binding	ISO
phosphatidylinositol-3,4,5-trisphosphate binding	IEA
phosphatidylinositol-3,5-bisphosphate binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding [inference]

phosphatidylinositol phosphate binding [inference]

phosphatidylinositol-3,4,5-trisphosphate binding

phosphatidylinositol bisphosphate binding [inference]

phosphatidylinositol-3,5-bisphosphate binding

ion binding [inference]

anion binding [inference]

molecular function regulator activity [inference]

enzyme regulator activity [inference]

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

guanyl-nucleotide exchange factor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
regulation of ARF protein signal transduction

Displaying **all 5** entries
InterPro
Armadillo-type fold
Mon2/Sec7/BIG1-like, HUS domain
Sec7 domain superfamily
Sec7 domain
Sec7, C-terminal domain superfamily

Ortholog

Displaying entries **31 - 40** of 91 in total

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Species	Gene ID	Orthologous MAtrix
Tursiops truncatus	101326050	TURTR10527
Octodon degus	101592528	OCTDE09241
Mustela putorius furo	101680550	MUSPF14694
Heterocephalus glaber	101712137	HETGA03807
Ficedula albicollis	101807770	FICAL01215
Macaca fascicularis	101865219	MACFA43282
Melopsittacus undulatus	101876305	MELUD00581
Chrysemys picta bellii	101945422	CHRPI15828
Ictidomys tridecemlineatus	101975057	ICTTR16805
Chinchilla lanigera	102018732	CHILA18894