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Guidelines

MIRAGE

cell adhesion molecule L1 like

Summary

Gene Symbol

CHL1

Organism

Homo sapiens (human)

External Links

NCBI Gene

10752

PubChem

10752

Alliance of Genome Resources

HGNC:1939

Annotation

Keyword

Alternative splicing
Cell adhesion
Cell membrane
Developmental protein
Differentiation
Disulfide bond
Extracellular matrix
Glycoprotein
Immunoglobulin domain
Neurogenesis
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
O00533	Close homolog of L1
A0A087X0M8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
neuron migration	IEA
cell adhesion	IEA
signal transduction	TAS	9799093
axon guidance	IEA
adult locomotory behavior	IEA

GO Hierarchy

biological process

cellular process [inference]

cell motility [inference]

cell migration [inference]

neuron migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition

behavior [inference]

locomotory behavior [inference]

adult locomotory behavior

adult behavior [inference]

adult locomotory behavior

exploration behavior

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of cellular process [inference]

signal transduction

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of neuron apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
plasma membrane	IEA
membrane	TAS	9799093
dendrite	IEA
neuron projection	IBA
apical part of cell	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

dendrite

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

apical part of cell

Displaying 1 entry
GO Term	Evidence Code	PMID
protease binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding [inference]

protease binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cell adhesion molecule

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
brain development
cell-cell adhesion mediator activity

Displaying **all 9** entries
InterPro
Fibronectin type III superfamily
Fibronectin type III
Immunoglobulin I-set
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
Neurofascin/L1/NrCAM, C-terminal domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:5419	schizophrenia	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 89 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	3897	FB:FBgn0264975
Drosophila melanogaster	4897	FB:FBgn0264975
Danio rerio	10752	ZFIN:ZDB-GENE-091105-1
Mus musculus	12661	ZFIN:ZDB-GENE-091105-1	MOUSE49345
Drosophila melanogaster	16728	FB:FBgn0264975
Drosophila melanogaster	23114	FB:FBgn0264975
Danio rerio	31792	ZFIN:ZDB-GENE-091105-1
Drosophila melanogaster	50687	FB:FBgn0264975
Rattus norvegicus	89828		RATNO31983
Drosophila melanogaster	116690	FB:FBgn0264975

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Last updated: December 8, 2025