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MIRAGE

TRAF3 interacting protein 2

Summary

Gene Symbol

TRAF3IP2

Organism

Homo sapiens (human)

External Links

NCBI Gene

10758

PubChem

10758

Alliance of Genome Resources

HGNC:1343

JoGo

TRAF3IP2

TogoVar

TRAF3IP2

Annotation

Keyword

Alternative splicing
Disease variant
Inflammatory response
Proteomics identification
Reference proteome
Transferase
Ubl conjugation pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
O43734	Adapter protein CIKS Connection to IKK and SAPK/JNK E3 ubiquitin-protein ligase CIKS Nuclear factor NF-kappa-B activator 1 TRAF3-interacting protein 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **16 - 20** of 34 in total

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GO Term	Evidence Code	PMID
CD40 signaling pathway	IEA
T cell differentiation	IEA
tumor necrosis factor-mediated signaling pathway	IEA
intracellular signal transduction	NAS	10962033
interleukin-17A-mediated signaling pathway	IDA	17277779 19825828

GO Hierarchy

biological process

immune system process [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

B cell homeostasis

eosinophil homeostasis

immune effector process [inference]

leukocyte mediated immunity [inference]

myeloid leukocyte mediated immunity [inference]

eosinophil mediated immunity

myeloid cell homeostasis [inference]

eosinophil homeostasis

B cell selection [inference]

peripheral B cell selection [inference]

B cell affinity maturation

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

T-helper 17 type immune response

leukocyte activation [inference]

leukocyte activation involved in inflammatory response

myeloid leukocyte activation [inference]

granulocyte activation [inference]

neutrophil activation

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation [inference]

immature B cell differentiation [inference]

transitional stage B cell differentiation [inference]

transitional two stage B cell differentiation

T cell differentiation

T cell activation [inference]

T cell differentiation

B cell activation [inference]

B cell differentiation [inference]

immature B cell differentiation [inference]

transitional stage B cell differentiation [inference]

transitional two stage B cell differentiation

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination [inference]

protein polyubiquitination [inference]

protein K63-linked ubiquitination

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination [inference]

protein polyubiquitination [inference]

protein K63-linked ubiquitination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination [inference]

protein polyubiquitination [inference]

protein K63-linked ubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination [inference]

protein polyubiquitination [inference]

protein K63-linked ubiquitination

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination [inference]

protein polyubiquitination [inference]

protein K63-linked ubiquitination

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

leukocyte activation involved in inflammatory response

myeloid leukocyte activation [inference]

granulocyte activation [inference]

neutrophil activation

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation [inference]

immature B cell differentiation [inference]

transitional stage B cell differentiation [inference]

transitional two stage B cell differentiation

T cell differentiation

T cell activation [inference]

T cell differentiation

B cell activation [inference]

B cell differentiation [inference]

immature B cell differentiation [inference]

transitional stage B cell differentiation [inference]

transitional two stage B cell differentiation

establishment or maintenance of cell polarity [inference]

establishment of cell polarity [inference]

establishment of lymphocyte polarity [inference]

establishment of T cell polarity

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

CD40 signaling pathway

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

leukocyte apoptotic process [inference]

lymphocyte apoptotic process [inference]

B cell apoptotic process

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation [inference]

immature B cell differentiation [inference]

transitional stage B cell differentiation [inference]

transitional two stage B cell differentiation

T cell differentiation

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

protein localization to P-body

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

leukocyte activation involved in inflammatory response

myeloid leukocyte activation [inference]

granulocyte activation [inference]

neutrophil activation

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation [inference]

immature B cell differentiation [inference]

transitional stage B cell differentiation [inference]

transitional two stage B cell differentiation

T cell differentiation

T cell activation [inference]

T cell differentiation

B cell activation [inference]

B cell differentiation [inference]

immature B cell differentiation [inference]

transitional stage B cell differentiation [inference]

transitional two stage B cell differentiation

secretion by tissue [inference]

mucus secretion

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

B cell homeostasis

eosinophil homeostasis

myeloid cell homeostasis [inference]

eosinophil homeostasis

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

hematopoietic or lymphoid organ development [inference]

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation [inference]

immature B cell differentiation [inference]

transitional stage B cell differentiation [inference]

transitional two stage B cell differentiation

T cell differentiation

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

B cell homeostasis

eosinophil homeostasis

myeloid cell homeostasis [inference]

eosinophil homeostasis

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

T-helper 17 type immune response

response to chemical [inference]

response to xenobiotic stimulus

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

protein localization to P-body

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of localization [inference]

transport [inference]

secretion [inference]

body fluid secretion [inference]

mucus secretion

secretion by tissue [inference]

mucus secretion

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

protein localization to P-body

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of macromolecule metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of cellular catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of RNA metabolic process [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of mRNA metabolic process [inference]

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of cellular catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of RNA metabolic process [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of mRNA metabolic process [inference]

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of macromolecule metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of RNA metabolic process [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of mRNA metabolic process [inference]

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of RNA metabolic process [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of mRNA metabolic process [inference]

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of macromolecule metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

regulation of defense response to virus [inference]

regulation of defense response to virus by host [inference]

positive regulation of defense response to virus by host

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of response to external stimulus [inference]

regulation of defense response to virus [inference]

regulation of defense response to virus by host [inference]

positive regulation of defense response to virus by host

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of defense response to virus [inference]

regulation of defense response to virus by host [inference]

positive regulation of defense response to virus by host

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

CD40 signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of RNA metabolic process [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of mRNA metabolic process [inference]

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of cellular catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA catabolic process [inference]

RNA stabilization [inference]

mRNA stabilization

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA catabolic process [inference]

mRNA stabilization

regulation of biological quality [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA stabilization

RNA stabilization [inference]

mRNA stabilization

regulation of body fluid levels [inference]

body fluid secretion [inference]

mucus secretion

Displaying **all 4** entries
GO Term	Evidence Code	PMID
nucleus	IEA
cytoplasm	IC	20554964
extrinsic component of cytoplasmic side of plasma membrane	IC	20554964
cytoplasmic vesicle	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

extrinsic component of membrane [inference]

extrinsic component of plasma membrane [inference]

extrinsic component of cytoplasmic side of plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle

Displaying **all 3** entries
GO Term	Evidence Code	PMID
signaling receptor binding	IEA
protein binding	IPI	12459498 21516116 24120361 25416956
ubiquitin protein ligase activity	IDA	19825828

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity [inference]

ubiquitin protein ligase activity

ubiquitin-like protein ligase activity [inference]

ubiquitin protein ligase activity

catalytic activity, acting on a protein [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity [inference]

ubiquitin protein ligase activity

ubiquitin-like protein ligase activity [inference]

ubiquitin protein ligase activity

binding [inference]

protein binding

signaling receptor binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

E3 ubiquitin ligase TRAF3IP2

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
humoral immune response
positive regulation of canonical NF-kappaB signal transduction

Displaying 1 entry
InterPro
SEFIR domain

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0111287	psoriasis 13	Alliance of Genome Resources
DOID:2058	chronic mucocutaneous candidiasis	Alliance of Genome Resources

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025