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solute carrier family 17 member 3

Summary

Gene Symbol

SLC17A3

Organism

Homo sapiens (human)

External Links

NCBI Gene

10786

PubChem

10786

Alliance of Genome Resources

HGNC:10931

Annotation

Keyword

Alternative splicing
Cell membrane
Endoplasmic reticulum
Glycoprotein
Reference proteome
Sodium transport
Symport
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O00476	Na(+)/PI cotransporter 4 Sodium/phosphate cotransporter 4 Solute carrier family 17 member 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
phosphate ion transport	ISS
glucose-6-phosphate transport	TAS	15505377
sodium ion transport	ISS
ion transmembrane transport	TAS
urate transport	IBA IDA	20810651

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

urate metabolic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

urate metabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

purine-containing compound metabolic process [inference]

urate metabolic process

cellular nitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

urate metabolic process

heterocycle metabolic process [inference]

purine-containing compound metabolic process [inference]

urate metabolic process

small molecule metabolic process [inference]

urate metabolic process

organic substance metabolic process [inference]

organic cyclic compound metabolic process [inference]

purine-containing compound metabolic process [inference]

urate metabolic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

urate metabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

purine-containing compound metabolic process [inference]

urate metabolic process

cellular nitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

urate metabolic process

heterocycle metabolic process [inference]

purine-containing compound metabolic process [inference]

urate metabolic process

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

monoatomic anion transmembrane transport

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

export across plasma membrane [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export from cell [inference]

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export across plasma membrane [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

monoatomic anion transport

monoatomic anion transmembrane transport

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

monoatomic anion transmembrane transport

inorganic anion transport [inference]

phosphate ion transport

xenobiotic transport [inference]

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

monoatomic anion transmembrane transport

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

export across plasma membrane [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

organic substance transport [inference]

organic anion transport

urate transport

organophosphate ester transport [inference]

hexose phosphate transport [inference]

glucose-6-phosphate transport

carbohydrate derivative transport [inference]

hexose phosphate transport [inference]

glucose-6-phosphate transport

nitrogen compound transport [inference]

urate transport

export from cell [inference]

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export across plasma membrane [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

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GO Term	Evidence Code	PMID
apical plasma membrane	IBA IDA	20810651
endoplasmic reticulum membrane	IDA TAS	15505377
plasma membrane	IBA IDA TAS	20810651
brush border membrane	ISS
perinuclear region of cytoplasm	IDA	15505377

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

plasma membrane region [inference]

apical plasma membrane

cell projection membrane [inference]

brush border membrane

perinuclear region of cytoplasm

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
organic anion transmembrane transporter activity	IDA	20810651
voltage-gated monoatomic anion channel activity	IBA IDA	20810651
xenobiotic transmembrane transporter activity	IBA IDA	20810651
toxin transmembrane transporter activity	IBA IDA	20810651
urate transmembrane transporter activity	IBA IDA TAS	20810651

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic anion transmembrane transporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic anion channel activity

monoatomic anion channel activity [inference]

voltage-gated monoatomic anion channel activity

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

monoatomic anion transmembrane transporter activity [inference]

monoatomic anion channel activity [inference]

voltage-gated monoatomic anion channel activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic anion channel activity

monoatomic anion channel activity [inference]

voltage-gated monoatomic anion channel activity

gated channel activity [inference]

voltage-gated channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic anion channel activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

xenobiotic transmembrane transporter activity

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

urate transmembrane transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

transporter

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
MFS transporter superfamily
Major facilitator superfamily domain
Major facilitator superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:13189	gout	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 53 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	35521		FB:FBgn0033048
Drosophila melanogaster	35745		FB:FBgn0033234
Drosophila melanogaster	37287		FB:FBgn0034490
Drosophila melanogaster	37624		FB:FBgn0034783
Drosophila melanogaster	37626		FB:FBgn0034785
Drosophila melanogaster	43761		FB:FBgn0039886
Mus musculus	105355		MGI:2389216	MOUSE10455
Rattus norvegicus	266730		RGD:628815	RATNO12658
Pan troglodytes	462488	9598_0:001f3f		PANTR37383
Bos taurus	519345			BOVIN19071