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phosphatidylinositol-5-phosphate 4-kinase, type II, beta

Summary

Gene Symbol

Pip4k2b

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

108083

PubChem

108083

Alliance of Genome Resources

MGI:1934234

Annotation

Keyword

ATP-binding
Acetylation
Cell membrane
Cytoplasm
Direct protein sequencing
Endoplasmic reticulum
GTP-binding
Kinase
Lipid metabolism
Nucleus
Phosphoprotein
Reference proteome
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3UJ95
Q80XI4	1-phosphatidylinositol 5-phosphate 4-kinase 2-beta Diphosphoinositide kinase 2-beta Phosphatidylinositol 5-phosphate 4-kinase type II beta PtdIns(5)P-4-kinase isoform 2-beta

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

1

2

3

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Last »
GO Term	Evidence Code	PMID
regulation of autophagy	ISO
regulation of autophagy	IMP	29727621
phosphatidylinositol metabolic process	IDA	9038203
negative regulation of insulin receptor signaling pathway	ISS
negative regulation of insulin receptor signaling pathway	ISO

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phosphatidylinositol metabolic process

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process [inference]

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phosphatidylinositol metabolic process

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process [inference]

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phosphatidylinositol metabolic process

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process [inference]

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phosphatidylinositol metabolic process

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process [inference]

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phosphatidylinositol metabolic process

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process [inference]

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phosphatidylinositol metabolic process

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process [inference]

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phosphatidylinositol metabolic process

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process [inference]

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phosphatidylinositol metabolic process

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process [inference]

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phosphatidylinositol metabolic process

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process [inference]

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phosphatidylinositol metabolic process

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process [inference]

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phosphatidylinositol metabolic process

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process [inference]

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phosphatidylinositol metabolic process

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process [inference]

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

phosphatidylinositol metabolic process

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process [inference]

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vesicle organization [inference]

vesicle fusion [inference]

autophagosome-lysosome fusion

organelle fusion [inference]

organelle membrane fusion [inference]

vesicle fusion [inference]

autophagosome-lysosome fusion

membrane organization [inference]

membrane fusion [inference]

organelle membrane fusion [inference]

vesicle fusion [inference]

autophagosome-lysosome fusion

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of autophagosome assembly

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of autophagosome assembly

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of autophagosome assembly

regulation of cellular catabolic process [inference]

regulation of autophagy

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of autophagosome assembly

regulation of macroautophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of autophagosome assembly

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of autophagosome assembly

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of autophagosome assembly

regulation of cellular catabolic process [inference]

regulation of autophagy

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of autophagosome assembly

regulation of macroautophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of autophagosome assembly

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of autophagosome assembly

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin receptor signaling pathway

regulation of insulin receptor signaling pathway [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin receptor signaling pathway

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of autophagosome assembly

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of autophagosome assembly

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of autophagosome assembly

positive regulation of cellular component biogenesis [inference]

positive regulation of organelle assembly [inference]

positive regulation of autophagosome assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of vacuole organization [inference]

positive regulation of autophagosome assembly

positive regulation of organelle assembly [inference]

positive regulation of autophagosome assembly

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of cellular response to insulin stimulus [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of cellular response to insulin stimulus [inference]

negative regulation of insulin receptor signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin receptor signaling pathway

regulation of insulin receptor signaling pathway [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of cellular response to insulin stimulus [inference]

negative regulation of insulin receptor signaling pathway

regulation of cellular response to insulin stimulus [inference]

negative regulation of cellular response to insulin stimulus [inference]

negative regulation of insulin receptor signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin receptor signaling pathway

regulation of insulin receptor signaling pathway [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin receptor signaling pathway

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of autophagosome assembly

regulation of cellular catabolic process [inference]

regulation of autophagy

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of autophagosome assembly

regulation of macroautophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of autophagosome assembly

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of autophagosome assembly

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of organelle assembly [inference]

positive regulation of autophagosome assembly

regulation of organelle assembly [inference]

positive regulation of organelle assembly [inference]

positive regulation of autophagosome assembly

regulation of autophagosome assembly [inference]

positive regulation of autophagosome assembly

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of autophagosome assembly

positive regulation of cellular component biogenesis [inference]

positive regulation of organelle assembly [inference]

positive regulation of autophagosome assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of vacuole organization [inference]

positive regulation of autophagosome assembly

positive regulation of organelle assembly [inference]

positive regulation of autophagosome assembly

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of cellular response to insulin stimulus [inference]

negative regulation of insulin receptor signaling pathway

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of vacuole organization [inference]

positive regulation of autophagosome assembly

positive regulation of organelle assembly [inference]

positive regulation of autophagosome assembly

regulation of vacuole organization [inference]

positive regulation of vacuole organization [inference]

positive regulation of autophagosome assembly

regulation of autophagosome assembly [inference]

positive regulation of autophagosome assembly

regulation of organelle assembly [inference]

positive regulation of organelle assembly [inference]

positive regulation of autophagosome assembly

regulation of autophagosome assembly [inference]

positive regulation of autophagosome assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of vacuole organization [inference]

positive regulation of autophagosome assembly

positive regulation of organelle assembly [inference]

positive regulation of autophagosome assembly

regulation of cellular response to insulin stimulus [inference]

negative regulation of cellular response to insulin stimulus [inference]

negative regulation of insulin receptor signaling pathway

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
nucleus	ISO
nucleoplasm	ISO
nucleoplasm	IEA
autophagosome	ISO
autophagosome	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

nucleoplasm

membrane [inference]

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

vacuole [inference]

autophagosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

vacuole [inference]

autophagosome

Displaying entries **1 - 5** of 11 in total

1

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GO Term	Evidence Code	PMID
protein binding	IPI	9038203
ATP binding	ISS
ATP binding	ISO
GTP binding	ISS
GTP binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

lipid kinase activity [inference]

phosphatidylinositol kinase activity [inference]

phosphotransferase activity, alcohol group as acceptor [inference]

phosphatidylinositol kinase activity [inference]

binding [inference]

protein binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GTP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GTP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

phosphatidylinositol 5-phosphate 4-kinase

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
1-phosphatidylinositol-5-phosphate 4-kinase activity
ATP binding
kinase activity
nucleotide binding
phosphatidylinositol kinase activity
phosphorylation
transferase activity

Displaying **all 4** entries
InterPro
Phosphatidylinositol-4-phosphate 4/5-kinase, C-terminal domain superfamily
Phosphatidylinositol-4-phosphate 4/5-kinase, core
Phosphatidylinositol-4-phosphate 5-kinase, N-terminal
Phosphatidylinositol-4/5-phosphate 5/4-kinase

Ortholog

Displaying entries **1 - 10** of 90 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	5305	SGD:S000002616
Saccharomyces cerevisiae S288C	8394	SGD:S000002616
Saccharomyces cerevisiae S288C	8395	SGD:S000002616
Homo sapiens	8396	Xenbase:XB-GENE-979374	HUMAN33271
Saccharomyces cerevisiae S288C	18717	SGD:S000002616
Saccharomyces cerevisiae S288C	18718	SGD:S000002616
Saccharomyces cerevisiae S288C	23396	SGD:S000002616
Saccharomyces cerevisiae S288C	79837	SGD:S000002616
Rattus norvegicus	89812		RATNO01223
Xenopus tropicalis	108083	Xenbase:XB-GENE-979374

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Acknowledgements