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heat shock protein family H (Hsp110) member 1

Summary

Gene Symbol

HSPH1

Organism

Homo sapiens (human)

External Links

NCBI Gene

10808

PubChem

10808

Alliance of Genome Resources

HGNC:16969

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Alternative splicing
Cytoplasm
Direct protein sequencing
Phosphoprotein
Proteomics identification
Reference proteome
Stress response

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q92598	Antigen NY-CO-25 Heat shock 110 kDa protein Heat shock protein family H member 1
A0A0A0MSM0
B4DY72

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
positive regulation of MHC class I biosynthetic process	TAS	12952910
response to unfolded protein	TAS	9931472
protein folding	IBA
chaperone cofactor-dependent protein refolding	IEA
positive regulation of NK T cell activation	TAS	12952910

GO Hierarchy

biological process

cellular process [inference]

protein folding

'de novo' protein folding [inference]

'de novo' post-translational protein folding [inference]

chaperone cofactor-dependent protein refolding

chaperone-mediated protein folding [inference]

chaperone cofactor-dependent protein refolding

response to stimulus [inference]

response to stress [inference]

response to topologically incorrect protein [inference]

response to unfolded protein

response to chemical [inference]

response to organic substance [inference]

response to topologically incorrect protein [inference]

response to unfolded protein

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

regulation of lymphocyte activation [inference]

regulation of T cell activation [inference]

regulation of alpha-beta T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

regulation of NK T cell activation [inference]

positive regulation of NK T cell activation

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

regulation of MHC class I biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

regulation of MHC class I biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

regulation of MHC class I biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

positive regulation of multicellular organismal process [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

regulation of cellular process [inference]

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

regulation of MHC class I biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of MHC class I biosynthetic process

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

regulation of lymphocyte activation [inference]

regulation of T cell activation [inference]

regulation of alpha-beta T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

regulation of NK T cell activation [inference]

positive regulation of NK T cell activation

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

regulation of lymphocyte activation [inference]

regulation of T cell activation [inference]

regulation of alpha-beta T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

regulation of NK T cell activation [inference]

positive regulation of NK T cell activation

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

positive regulation of multicellular organismal process [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of T cell activation [inference]

positive regulation of alpha-beta T cell activation [inference]

positive regulation of NK T cell activation

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
nucleus	IBA
protein-containing complex	IDA	23349634
cytoplasm	IDA	9931472
extracellular region	TAS	12952910
nucleoplasm	IDA

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endocytic vesicle lumen

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

nucleus

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying **all 5** entries
GO Term	Evidence Code	PMID
adenyl-nucleotide exchange factor activity	IBA IDA	24318877
ATP binding	IEA
protein binding	IPI	17024176 23349634 24318877 25036637
ATP-dependent protein folding chaperone	IEA
alpha-tubulin binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

alpha-tubulin binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl-nucleotide exchange factor activity

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl-nucleotide exchange factor activity

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

protein folding chaperone [inference]

ATP-dependent protein folding chaperone

molecular function regulator activity [inference]

ATPase regulator activity [inference]

adenyl-nucleotide exchange factor activity

ATP-dependent activity [inference]

ATP-dependent protein folding chaperone

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **51 - 60** of 64 in total

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Species	Gene ID	Orthologous MAtrix
Cercocebus atys	105587905	CERAT09976
Aotus nancymaae	105732124	AOTNA36108
Equus asinus asinus	106835534	EQUAS11995
Crocodylus porosus	109306610	CROPO03071
Pseudonaja textilis	113441708	PSETE13799
Athene cunicularia	113478106	ATHCN02535
Bos indicus x Bos taurus	113902334	BOBOX42366
Vombatus ursinus	114022781	VOMUR10071
Strigops habroptila	115604189	STRHB01033
Corvus moneduloides	116439679	CORMO15829

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