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CEA cell adhesion molecule 8

Summary

Gene Symbol

CEACAM8

Organism

Homo sapiens (human)

External Links

NCBI Gene

1088

PubChem

1088

Alliance of Genome Resources

HGNC:1820

Annotation

Keyword

3D-structure
Cell adhesion
Cell membrane
Disulfide bond
GPI-anchor
Immunoglobulin domain
Reference proteome
Repeat
Signal

Proteins

Displaying **all 3** entries
UniProt	Protein Name
B4DLI3
P31997	CD67 antigen Carcinoembryonic antigen CGM6 Non-specific cross-reacting antigen NCA-95
Q0Z7S6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
immune response	TAS	2208113
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IMP	11590190 8776764
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IBA

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

response to stimulus [inference]

immune response

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
extracellular space	IDA	25645918
plasma membrane	TAS
cell surface	IDA	8776764
cell surface	IBA
azurophil granule membrane	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane [inference]

azurophil granule membrane

secretory granule membrane [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

side of membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	11994468 21982860 26483485
protein heterodimerization activity	IDA	26483485

GO Hierarchy

molecular function

binding [inference]

protein binding

protein dimerization activity [inference]

protein heterodimerization activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Opioid-binding protein/cell adhesion molecule

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 5** entries
InterPro
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold

Ortholog

Displaying entries **1 - 10** of 36 in total

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Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	634	Xenbase:XB-GENE-22169429
Xenopus tropicalis	1048	Xenbase:XB-GENE-5920801
Xenopus tropicalis	1087	Xenbase:XB-GENE-22169429
Xenopus tropicalis	1088	Xenbase:XB-GENE-22169429
Xenopus tropicalis	1089	Xenbase:XB-GENE-22169429
Xenopus tropicalis	4680	Xenbase:XB-GENE-5920801
Xenopus tropicalis	5669	Xenbase:XB-GENE-22169429
Xenopus tropicalis	5670	Xenbase:XB-GENE-5920801
Xenopus tropicalis	5671	Xenbase:XB-GENE-22169429
Xenopus tropicalis	5672	Xenbase:XB-GENE-22169429