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neuropeptide FF receptor 2

Summary

Gene Symbol

NPFFR2

Organism

Homo sapiens (human)

External Links

NCBI Gene

10886

PubChem

10886

Alliance of Genome Resources

HGNC:4525

Annotation

Keyword

Alternative splicing
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A804CC06
Q9Y5X5	G-protein coupled receptor 74 G-protein coupled receptor HLWAR77 Neuropeptide G-protein coupled receptor
A0PJM9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
G protein-coupled receptor signaling pathway	IBA
neuropeptide signaling pathway	IDA	11024015
detection of abiotic stimulus	TAS	10851242
cellular response to hormone stimulus	IBA
regulation of MAPK cascade	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

neuropeptide signaling pathway

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus

response to stimulus [inference]

response to abiotic stimulus [inference]

detection of abiotic stimulus

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

cellular response to hormone stimulus

cellular response to organic substance [inference]

cellular response to hormone stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus

detection of stimulus [inference]

detection of abiotic stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of cellular metabolic process [inference]

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cAMP-dependent protein kinase activity

regulation of kinase activity [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cAMP-dependent protein kinase activity

regulation of nitrogen compound metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cAMP-dependent protein kinase activity

regulation of macromolecule metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cAMP-dependent protein kinase activity

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cAMP-dependent protein kinase activity

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

neuropeptide signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade

regulation of cellular metabolic process [inference]

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cAMP-dependent protein kinase activity

regulation of kinase activity [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cAMP-dependent protein kinase activity

regulation of molecular function [inference]

regulation of catalytic activity [inference]

regulation of cyclase activity [inference]

regulation of adenylate cyclase activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

regulation of protein kinase activity [inference]

regulation of protein serine/threonine kinase activity [inference]

regulation of cAMP-dependent protein kinase activity

regulation of lyase activity [inference]

regulation of adenylate cyclase activity

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IDA	11024015
plasma membrane	IBA
actin cytoskeleton	IDA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

Displaying **all 5** entries
GO Term	Evidence Code	PMID
G protein-coupled receptor activity	IBA
protein binding	IPI	32296183
neuropeptide receptor activity	IDA	11024015
opioid receptor binding	IEA
peptide binding

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

opioid receptor binding

amide binding [inference]

peptide binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

receptor

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
neuropeptide receptor activity
neuropeptide signaling pathway

Displaying **all 2** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Ortholog

Displaying entries **81 - 89** of 89 in total

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Species	Gene ID	Orthologous MAtrix
Sparus aurata	115582268	SPAAU14326
Strigops habroptila	115604691	STRHB22469
Corvus moneduloides	116444793	CORMO21931
Chelonoidis abingdonii	116817710	CHEAB12908
Rhinolophus ferrumequinum	117022383	RHIFE19256
Scophthalmus maximus	118313903	SCOMX33475
Balaenoptera musculus	118896000	BALMU28023
Panthera leo	122217120	PANLE26974
Ursus americanus	123789407	URSAM24534