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Guidelines

MIRAGE

poly(A) polymerase alpha

Summary

Gene Symbol

PAPOLA

Organism

Homo sapiens (human)

External Links

NCBI Gene

10914

KEGG Gene ID

PubChem

10914

Alliance of Genome Resources

HGNC:14981

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Alternative splicing
Cytoplasm
Isopeptide bond
Magnesium
Manganese
Metal-binding
Nucleus
Phosphoprotein
Proteomics identification
RNA-binding
Reference proteome
Transferase
Ubl conjugation
mRNA processing

Proteins

Displaying **all 3** entries
UniProt	Protein Name
G3XAH6
A0A0C4DGK1
P51003	Polynucleotide adenylyltransferase alpha

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
mRNA processing
RNA 3'-end processing	IEA
mRNA 3'-end processing	IDA
co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway	TAS
co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway	IDA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA processing

mRNA 3'-end processing

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

cytosolic mRNA polyadenylation

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA processing

mRNA 3'-end processing

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

cytosolic mRNA polyadenylation

RNA processing [inference]

mRNA processing

mRNA 3'-end processing

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

RNA 3'-end processing

mRNA 3'-end processing

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway [inference]

co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
nucleus	TAS
nucleus	IDA
nucleus	IBA
nucleus	IEA
nucleoplasm	TAS

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
magnesium ion binding	ISS
RNA binding	IEA
protein binding	IPI
ATP binding	ISS
ATP binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity

adenylyltransferase activity [inference]

poly(A) RNA polymerase activity

binding [inference]

nucleic acid binding [inference]

RNA binding

protein binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

magnesium ion binding

transition metal ion binding [inference]

manganese ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Mus musculus	18789	MGI:109301

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026