GlyCosmos Portal

Annotation

Keyword

Acetylation
Alternative splicing
Endoplasmic reticulum
GTP-binding
Hydrolase
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q91YH5
E9PYT3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
Golgi organization	ISO ISS
endoplasmic reticulum organization	IBA ISO ISS
cellular response to type II interferon	IEA
positive regulation of endoplasmic reticulum tubular network organization	ISO ISS
protein homooligomerization	IBA ISO ISS

GO Hierarchy

biological process

cellular process [inference]

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to type II interferon

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

response to type II interferon [inference]

cellular response to type II interferon

cellular response to cytokine stimulus [inference]

cellular response to type II interferon

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to type II interferon

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to type II interferon

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to type II interferon

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of endoplasmic reticulum tubular network organization

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of endoplasmic reticulum tubular network organization

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of endoplasmic reticulum tubular network organization

regulation of endoplasmic reticulum tubular network organization [inference]

positive regulation of endoplasmic reticulum tubular network organization

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of endoplasmic reticulum tubular network organization

Displaying **all 4** entries
GO Term	Evidence Code	PMID
membrane	ISO ISS
endoplasmic reticulum tubular network membrane	ISO ISS
endoplasmic reticulum tubular network	ISO ISS
endoplasmic reticulum	ISO ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane [inference]

endoplasmic reticulum tubular network membrane

organelle subcompartment [inference]

endoplasmic reticulum subcompartment [inference]

endoplasmic reticulum tubular network

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IPI	32075961
GTPase activity	IBA IEA
identical protein binding	ISO ISS
GTP binding	IBA IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

binding [inference]

protein binding

identical protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Guanylate-binding protein, C-terminal domain superfamily

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
P: Inorganic ion transport and metabolism

Displaying **all 4** entries
Gene Ontology
GTP binding
cellular response to type II interferon
endoplasmic reticulum organization
protein homooligomerization

Displaying **all 5** entries
InterPro
GB1/RHD3-type guanine nucleotide-binding (G) domain
Guanylate-binding protein, C-terminal domain superfamily
Guanylate-binding protein, N-terminal
Guanylate-binding protein/Atlastin, C-terminal
P-loop containing nucleoside triphosphate hydrolase

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0070154	hereditary sensory neuropathy type 1F	Alliance of Genome Resources
DOID:0110791	hereditary spastic paraplegia 3A	Alliance of Genome Resources
DOID:2476	hereditary spastic paraplegia	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **108** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	25923		HGNC:24526	HUMAN06745
Drosophila melanogaster	42934		FB:FBgn0039213
Caenorhabditis elegans	177059		WB:WBGene00021868
Rattus norvegicus	309187	10116_1:00091f	RGD:1309871	RATNO19956
Danio rerio	449995		ZFIN:ZDB-GENE-041010-109
Pan troglodytes	451280			PANTR03223
Canis lupus familiaris	476044			CANLF06132
Bos taurus	515124			BOVIN23347
Xenopus tropicalis	549349		Xenbase:XB-GENE-1009682
Macaca mulatta	722170			MACMU10702

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements