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euchromatic histone lysine methyltransferase 2

Summary

Gene Symbol

EHMT2

Organism

Homo sapiens (human)

External Links

NCBI Gene

10919

PubChem

10919

Alliance of Genome Resources

HGNC:14129

Annotation

Keyword

3D-structure
ANK repeat
Acetylation
Alternative splicing
Chromatin regulator
Chromosome
Isopeptide bond
Metal-binding
Methylation
Methyltransferase
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
S-adenosyl-L-methionine
Ubl conjugation
Zinc

Proteins

Displaying **all 5** entries
UniProt	Protein Name
A2ABF8
Q96KQ7	Euchromatic histone-lysine N-methyltransferase 2 HLA-B-associated transcript 8 Histone H3-K9 methyltransferase 3 Lysine N-methyltransferase 1C Protein G9a
A0A024RCN9
B7Z852
Q59FM7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	PMID
negative regulation of transcription by RNA polymerase II	IDA	19144645
negative regulation of transcription by RNA polymerase II	IBA
regulation of DNA replication	IMP	22387026
DNA methylation-dependent heterochromatin formation	ISS
synaptonemal complex assembly	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine dimethylation

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine dimethylation

methylation [inference]

macromolecule methylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine dimethylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine dimethylation

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine dimethylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine dimethylation

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine dimethylation

macromolecule modification [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine dimethylation

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine dimethylation

macromolecule methylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine dimethylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine dimethylation

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine dimethylation

cellular process [inference]

cell communication [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cell cycle process [inference]

meiotic cell cycle process [inference]

chromosome organization involved in meiotic cell cycle [inference]

synaptonemal complex assembly

cellular process involved in reproduction in multicellular organism [inference]

germ cell development [inference]

phenotypic switching

cellular developmental process [inference]

cell fate specification [inference]

neuron fate specification

cell development [inference]

germ cell development [inference]

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to cocaine

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to cocaine

cellular response to xenobiotic stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to cocaine

cellular response to oxygen-containing compound [inference]

cellular response to cocaine

cellular response to salt [inference]

cellular response to cocaine

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

chromosome organization [inference]

chromosome organization involved in meiotic cell cycle [inference]

synaptonemal complex assembly

synaptonemal complex organization [inference]

synaptonemal complex assembly

cellular component assembly [inference]

synaptonemal complex assembly

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling [inference]

epigenetic regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

heterochromatin organization [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

reproductive process [inference]

developmental process involved in reproduction [inference]

germ cell development [inference]

fertilization

cellular process involved in reproduction in multicellular organism [inference]

germ cell development [inference]

meiotic cell cycle process [inference]

chromosome organization involved in meiotic cell cycle [inference]

synaptonemal complex assembly

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

memory [inference]

long-term memory

behavior [inference]

learning or memory [inference]

memory [inference]

long-term memory

adult behavior [inference]

behavioral response to cocaine

organ growth

developmental process [inference]

developmental process involved in reproduction [inference]

germ cell development [inference]

anatomical structure development [inference]

cell development [inference]

germ cell development [inference]

cellular developmental process [inference]

cell fate specification [inference]

neuron fate specification

cell development [inference]

germ cell development [inference]

growth [inference]

developmental growth [inference]

organ growth

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to external stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

response to endogenous stimulus [inference]

cellular response to endogenous stimulus [inference]

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to cocaine

response to chemical [inference]

response to xenobiotic stimulus [inference]

cellular response to xenobiotic stimulus

response to toxic substance [inference]

response to fungicide

response to organic substance [inference]

response to organonitrogen compound [inference]

response to alkaloid [inference]

response to cocaine [inference]

cellular response to cocaine

cellular response to alkaloid [inference]

cellular response to cocaine

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to cocaine

response to organic cyclic compound [inference]

response to cocaine [inference]

cellular response to cocaine

cellular response to organic cyclic compound [inference]

cellular response to cocaine

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to cocaine

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to cocaine

response to alcohol [inference]

response to ethanol

response to antibiotic [inference]

response to fungicide

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to cocaine

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to cocaine

cellular response to xenobiotic stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to cocaine

cellular response to oxygen-containing compound [inference]

cellular response to cocaine

cellular response to salt [inference]

cellular response to cocaine

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to alkaloid [inference]

response to cocaine [inference]

cellular response to cocaine

cellular response to alkaloid [inference]

cellular response to cocaine

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to cocaine

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to cocaine

response to oxygen-containing compound [inference]

response to cocaine [inference]

cellular response to cocaine

response to alcohol [inference]

response to ethanol

cellular response to oxygen-containing compound [inference]

cellular response to cocaine

response to salt [inference]

response to cocaine [inference]

cellular response to cocaine

cellular response to salt [inference]

cellular response to cocaine

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound [inference]

cellular response to cocaine

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to cocaine

cellular response to xenobiotic stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to cocaine

cellular response to oxygen-containing compound [inference]

cellular response to cocaine

cellular response to salt [inference]

cellular response to cocaine

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

epigenetic regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

regulation of macroautophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA metabolic process [inference]

regulation of DNA replication

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

epigenetic regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

regulation of macroautophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA metabolic process [inference]

regulation of DNA replication

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

epigenetic regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA metabolic process [inference]

regulation of DNA replication

regulation of protein metabolic process [inference]

regulation of protein modification process

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA metabolic process [inference]

regulation of DNA replication

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of organelle assembly [inference]

negative regulation of autophagosome assembly

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA metabolic process [inference]

regulation of DNA replication

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

epigenetic regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

regulation of macroautophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

regulation of cellular component biogenesis [inference]

regulation of organelle assembly [inference]

negative regulation of organelle assembly [inference]

negative regulation of autophagosome assembly

regulation of autophagosome assembly [inference]

negative regulation of autophagosome assembly

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

facultative heterochromatin formation [inference]

DNA methylation-dependent heterochromatin formation

negative regulation of gene expression via CpG island methylation

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of organelle assembly [inference]

negative regulation of autophagosome assembly

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

negative regulation of organelle organization [inference]

negative regulation of organelle assembly [inference]

negative regulation of autophagosome assembly

regulation of vacuole organization [inference]

regulation of autophagosome assembly [inference]

negative regulation of autophagosome assembly

regulation of organelle assembly [inference]

negative regulation of organelle assembly [inference]

negative regulation of autophagosome assembly

regulation of autophagosome assembly [inference]

negative regulation of autophagosome assembly

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of organelle assembly [inference]

negative regulation of autophagosome assembly

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GO Term	Evidence Code	PMID
chromatin	IDA	19144645
chromatin	IBA
nucleus	ISS
nucleus	IDA	19144645
nucleus	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-DNA complex [inference]

chromatin

cellular anatomical entity [inference]

nucleoplasm

nuclear body [inference]

nuclear speck

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
RNA polymerase II transcription regulatory region sequence-specific DNA binding	IEA
transcription corepressor binding	IPI	29628311
p53 binding	IPI	20118233
protein binding	IPI	16189514 16287849 16702210 17636019 18451879 18953337 19061646 21549307 23752268 24492005 25910212 26028330 26751641 26871637 27339988 27705803 29774127 32296183 33961781 35140242
zinc ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity [inference]

N-methyltransferase activity [inference]

lysine N-methyltransferase activity [inference]

protein-lysine N-methyltransferase activity

histone H3K9 methyltransferase activity

histone H3K9me2 methyltransferase activity

protein methyltransferase activity [inference]

protein-lysine N-methyltransferase activity

histone H3K9 methyltransferase activity

histone H3K9me2 methyltransferase activity

histone methyltransferase activity [inference]

histone H3 methyltransferase activity [inference]

histone H3K9 methyltransferase activity

histone H3K9me2 methyltransferase activity

S-adenosylmethionine-dependent methyltransferase activity [inference]

lysine N-methyltransferase activity [inference]

protein-lysine N-methyltransferase activity

histone H3K9 methyltransferase activity

histone H3K9me2 methyltransferase activity

catalytic activity, acting on a protein [inference]

protein methyltransferase activity [inference]

protein-lysine N-methyltransferase activity

histone H3K9 methyltransferase activity

histone H3K9me2 methyltransferase activity

histone methyltransferase activity [inference]

histone H3 methyltransferase activity [inference]

histone H3K9 methyltransferase activity

histone H3K9me2 methyltransferase activity

histone modifying activity [inference]

histone methyltransferase activity [inference]

histone H3 methyltransferase activity [inference]

histone H3K9 methyltransferase activity

histone H3K9me2 methyltransferase activity

binding [inference]

protein binding

p53 binding

transcription factor binding [inference]

transcription coregulator binding [inference]

transcription corepressor binding

protein domain specific binding [inference]

C2H2 zinc finger domain binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

protein-containing complex binding [inference]

chromatin binding [inference]

promoter-specific chromatin binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

transcription regulatory region nucleic acid binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding

DNA binding [inference]

double-stranded DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding

sequence-specific DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

histone-lysine N-methyltransferase

Functional Category

J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms
V: Defense mechanisms

Displaying **all 2** entries
Gene Ontology
histone methyltransferase activity
zinc ion binding

Displaying **all 3** entries
InterPro
Pre-SET domain
SET domain superfamily
SET domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050156	idiopathic pulmonary fibrosis	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 55 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	10919	Xenbase:XB-GENE-487387
Drosophila melanogaster	77683	FB:FBgn0040372
Drosophila melanogaster	79813	FB:FBgn0040372
Mus musculus	110147		MOUSE20525
Rattus norvegicus	361798		RATNO22644
Pan troglodytes	462572		PANTR37751
Canis lupus familiaris	474851		CANLF02573
Danio rerio	569250		DANRE16508
Macaca mulatta	715824		MACMU35156
Sus scrofa	100124382		PIGXX31202

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements