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oxoglutarate dehydrogenase

Summary

Gene Symbol

OGDH

Organism

Panthera pardus (leopard)

External Links

NCBI Gene: 109267927
KEGG Gene ID: ppad:109267927
PubChem: 109267927

Annotation

Keyword

Isopeptide bond
Nucleus
Oxidoreductase
Thiamine pyrophosphate
Transit peptide
Ubl conjugation

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A9V1FP64	2-oxoglutarate dehydrogenase, mitochondrial Alpha-ketoglutarate dehydrogenase Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase
A0A9V1FP57	2-oxoglutarate dehydrogenase, mitochondrial Alpha-ketoglutarate dehydrogenase Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase
A0A9V1FP83	2-oxoglutarate dehydrogenase, mitochondrial Alpha-ketoglutarate dehydrogenase Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
tricarboxylic acid cycle	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

tricarboxylic acid cycle

Displaying **all 2** entries
GO Term	Evidence Code	PMID
oxoglutarate dehydrogenase complex	IEA	30032202
mitochondrion	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

tricarboxylic acid cycle enzyme complex [inference]

dihydrolipoyl dehydrogenase complex [inference]

oxoglutarate dehydrogenase complex

oxidoreductase complex [inference]

dihydrolipoyl dehydrogenase complex [inference]

oxoglutarate dehydrogenase complex

transferase complex [inference]

oxoglutarate dehydrogenase complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 2** entries
GO Term	Evidence Code	PMID
oxoglutarate dehydrogenase (succinyl-transferring) activity	IEA	22301074 30032202
thiamine pyrophosphate binding	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor [inference]

oxoglutarate dehydrogenase (succinyl-transferring) activity

binding [inference]

small molecule binding [inference]

vitamin binding [inference]

thiamine pyrophosphate binding

quaternary ammonium group binding [inference]

thiamine pyrophosphate binding

heterocyclic compound binding [inference]

thiamine pyrophosphate binding

ion binding [inference]

anion binding [inference]

thiamine pyrophosphate binding

cation binding [inference]

thiamine pyrophosphate binding

organic cyclic compound binding [inference]

thiamine pyrophosphate binding

sulfur compound binding [inference]

thiamine pyrophosphate binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00164

Name

2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]

References

Rhea

H⁺ + 2-oxoglutarate

CO₂

Enzyme

1.2.4.2

PMID

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.0.0

Last updated: August 19, 2024