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MIRAGE

EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase

Summary

Gene Symbol

eogt

Organism

Hippocampus comes (tiger tail seahorse)

External Links

NCBI Gene: 109509878
KEGG Gene ID: hcq:109509878
PubChem: 109509878

Annotation

Keyword

Glycoprotein
Glycosyltransferase
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A3Q2YNM9	Extracellular O-linked N-acetylglucosamine transferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
protein O-GlcNAcylation via threonine	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

peptidyl-amino acid modification [inference]

peptidyl-threonine modification [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

peptidyl-amino acid modification [inference]

peptidyl-threonine modification [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

peptidyl-amino acid modification [inference]

peptidyl-threonine modification [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

peptidyl-amino acid modification [inference]

peptidyl-threonine modification [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

peptidyl-amino acid modification [inference]

peptidyl-threonine modification [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum lumen	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

Displaying 1 entry
GO Term	Evidence Code	PMID
protein N-acetylglucosaminyltransferase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

protein N-acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

protein N-acetylglucosaminyltransferase activity

catalytic activity, acting on a protein [inference]

protein N-acetylglucosaminyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

EGF domain-specific O-linked N-acetylglucosamine transferase

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
protein O-GlcNAcylation via threonine
protein O-acetylglucosaminyltransferase activity
transferase activity

Displaying **all 2** entries
InterPro
Glycosyltransferase 61, catalytic domain
Glycosyltransferase 61

KEGG BRITE Database

Orthology

K18134

Name

EGF domain-specific O-GlcNAc transferase [EC:2.4.1.255]

References

22158438

Rhea

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.255

PMID

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.255

PMID

Ortholog

Displaying entries **1 - 10** of 96 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	101351		MOUSE48836
Homo sapiens	285203		HUMAN70896
Rattus norvegicus	494219		RATNO31616
Pan troglodytes	494220		PANTR31528
Canis lupus familiaris	494221		CANLF07354
Ciona intestinalis	497240		CIOIN10572
Bos taurus	508782		BOVIN17521
Macaca mulatta	696742		MACMU29625
Takifugu rubripes	777950		TAKRU21695
Danio rerio	798087		DANRE02633

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025