GlyCosmos Portal

Submissions

glucuronidase, beta

Summary

Gene Symbol

Gusb

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

110006

PubChem

110006

Alliance of Genome Resources

MGI:95872

Annotation

Keyword

Endoplasmic reticulum
Glycoprotein
Glycosidase
Lysosome
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
P12265

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
carbohydrate metabolic process	IDA	4841576
heparan sulfate proteoglycan catabolic process	IMP	11273777 23897660
chondroitin sulfate catabolic process	IMP	23897660
hyaluronan catabolic process	ISO	6459778 7354065
hyaluronan catabolic process	IMP	20385825

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process [inference]

mucopolysaccharide metabolic process [inference]

chondroitin sulfate metabolic process [inference]

chondroitin sulfate catabolic process

hyaluronan metabolic process [inference]

hyaluronan catabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

protein catabolic process [inference]

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

catabolic process [inference]

cellular catabolic process [inference]

sulfur compound catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

cellular metabolic process [inference]

sulfur compound metabolic process [inference]

chondroitin sulfate metabolic process [inference]

chondroitin sulfate catabolic process

sulfur compound catabolic process [inference]

cellular catabolic process [inference]

sulfur compound catabolic process [inference]

primary metabolic process [inference]

carbohydrate metabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

protein catabolic process [inference]

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process [inference]

mucopolysaccharide metabolic process [inference]

chondroitin sulfate metabolic process [inference]

chondroitin sulfate catabolic process

hyaluronan metabolic process [inference]

hyaluronan catabolic process

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

protein catabolic process [inference]

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process [inference]

mucopolysaccharide metabolic process [inference]

chondroitin sulfate metabolic process [inference]

chondroitin sulfate catabolic process

hyaluronan metabolic process [inference]

hyaluronan catabolic process

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process [inference]

mucopolysaccharide metabolic process [inference]

chondroitin sulfate metabolic process [inference]

chondroitin sulfate catabolic process

hyaluronan metabolic process [inference]

hyaluronan catabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

protein catabolic process [inference]

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process [inference]

proteoglycan catabolic process [inference]

heparan sulfate proteoglycan catabolic process

cellular process [inference]

cellular metabolic process [inference]

sulfur compound metabolic process [inference]

chondroitin sulfate metabolic process [inference]

chondroitin sulfate catabolic process

sulfur compound catabolic process [inference]

cellular catabolic process [inference]

sulfur compound catabolic process [inference]

Displaying entries **1 - 5** of 8 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
extracellular space	ISO
extracellular space	IDA	19710420
extracellular space	IBA
lysosome	IDA	29514215 4841576 9774663
endoplasmic reticulum	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

lysosomal lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum

Displaying entries **1 - 5** of 12 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
beta-glucuronidase activity	ISO	6459778 7354065
beta-glucuronidase activity	IDA	1914521 19751987 4777306 4841576 7203014 8200966
beta-glucuronidase activity	IMP	11273777 20385825 9774663
beta-glucuronidase activity	IBA
signaling receptor binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

beta-glucuronidase activity

binding [inference]

protein binding [inference]

carbohydrate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

beta-glucuronidase

Functional Category

C: Energy production and conversion
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
beta-glucuronidase activity
glucuronoside catabolic process
hydrolase activity, acting on glycosyl bonds
hydrolase activity
signaling receptor binding

Displaying **all 10** entries
InterPro
Beta-Galactosidase/glucuronidase domain superfamily
Galactose-binding-like domain superfamily
Glycoside hydrolase family 2, catalytic domain
Glycoside hydrolase superfamily
Glycoside hydrolase, family 2, active site
Glycoside hydrolase, family 2, conserved site
Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich
Glycoside hydrolase, family 2
Glycosyl hydrolases family 2, sugar binding domain
Immunoglobulin-like fold

Rhea

RHEA:17633

H₂O + a β-D-glucuronoside

an alcohol + D-glucuronate

Enzyme

3.2.1.31

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:12803	mucopolysaccharidosis type VII	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP005176
Gene Name: glucuronidase, beta

Ortholog

Displaying entries **1 - 10** of 84 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	2990	Xenbase:XB-GENE-921780	HUMAN89133
Rattus norvegicus	24434	Xenbase:XB-GENE-921780	RATNO05850
Xenopus tropicalis	110006	Xenbase:XB-GENE-921780
Xenopus tropicalis	173326	Xenbase:XB-GENE-921780
Canis lupus familiaris	403831		CANLF16106
Pan troglodytes	463443		PANTR40393
Felis catus	493879		FELCA34869
Bos taurus	515687		BOVIN20685
Danio rerio	571441		DANRE36089
Macaca mulatta	677692		MACMU31053

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements