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liver glycogen phosphorylase

Summary

Gene Symbol

Pygl

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

110095

PubChem

110095

Alliance of Genome Resources

MGI:97829

Annotation

Keyword

Acetylation
Allosteric enzyme
Cytoplasm
Direct protein sequencing
Glycogen metabolism
Glycosyltransferase
Nucleotide-binding
Phosphoprotein
Pyridoxal phosphate
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9ET01

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
response to bacterium	IEP	23012479
glycogen catabolic process	IBA IMP ISO	31701076 36077341
glucose homeostasis	IEA ISO
glycogen metabolic process	ISO
necroptotic process	IGI	19498109

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

biosynthetic process [inference]

organic substance biosynthetic process [inference]

organophosphate biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

glycogen catabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

ribose phosphate metabolic process [inference]

ribose phosphate biosynthetic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

5-phosphoribose 1-diphosphate metabolic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

organophosphate metabolic process [inference]

ribose phosphate metabolic process [inference]

ribose phosphate biosynthetic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

5-phosphoribose 1-diphosphate metabolic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

glucan metabolic process [inference]

glycogen metabolic process

glycogen catabolic process

glucan catabolic process [inference]

glycogen catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

glucan metabolic process [inference]

glycogen metabolic process

glycogen catabolic process

glucan catabolic process [inference]

glycogen catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

organophosphate metabolic process [inference]

ribose phosphate metabolic process [inference]

ribose phosphate biosynthetic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

5-phosphoribose 1-diphosphate metabolic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

glucan metabolic process [inference]

glycogen metabolic process

glycogen catabolic process

glucan catabolic process [inference]

glycogen catabolic process

macromolecule catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

carbohydrate derivative metabolic process [inference]

ribose phosphate metabolic process [inference]

ribose phosphate biosynthetic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

5-phosphoribose 1-diphosphate metabolic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

organic substance biosynthetic process [inference]

organophosphate biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

cellular process [inference]

cell death [inference]

programmed cell death [inference]

programmed necrotic cell death [inference]

necroptotic process

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

glycogen catabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

ribose phosphate metabolic process [inference]

ribose phosphate biosynthetic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

5-phosphoribose 1-diphosphate metabolic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

organophosphate metabolic process [inference]

ribose phosphate metabolic process [inference]

ribose phosphate biosynthetic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

5-phosphoribose 1-diphosphate metabolic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

homeostatic process [inference]

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytosol	IEA
cytoplasm	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
vitamin binding	ISO
protein binding	IPI	19498109
purine nucleobase binding	IEA ISO
AMP binding	IEA ISO
SHG alpha-glucan phosphorylase activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

1,4-alpha-oligoglucan phosphorylase activity

glycogen phosphorylase activity

binding [inference]

protein binding

identical protein binding

carbohydrate binding

monosaccharide binding [inference]

glucose binding

small molecule binding [inference]

vitamin binding

vitamin B6 binding [inference]

pyridoxal phosphate binding

organic acid binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

bile acid binding

monosaccharide binding [inference]

glucose binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

nucleobase binding [inference]

purine nucleobase binding

vitamin B6 binding [inference]

pyridoxal phosphate binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

bile acid binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

AMP binding

organic cyclic compound binding [inference]

nucleobase binding [inference]

purine nucleobase binding

vitamin B6 binding [inference]

pyridoxal phosphate binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

glycogen phosphorylase, liver form

Functional Category

G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms
X: Mobilome: prophages, transposons

Displaying **all 10** entries
Gene Ontology
1,4-alpha-oligoglucan phosphorylase activity
SHG alpha-glucan phosphorylase activity
catalytic activity
glycogen catabolic process
glycogen metabolic process
glycogen phosphorylase activity
linear malto-oligosaccharide phosphorylase activity
nucleotide binding
pyridoxal phosphate binding
transferase activity

Displaying **all 3** entries
InterPro
Glycogen/starch/alpha-glucan phosphorylase
Glycosyl transferase, family 35
Phosphorylase pyridoxal-phosphate attachment site

Rhea

RHEA:41732

phosphate

α-D-glucose 1-phosphate

Enzyme

2.4.1.1

PMID

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:2747	glycogen storage disease	Alliance of Genome Resources
DOID:2754	glycogen storage disease VI	Alliance of Genome Resources
DOID:3650	lactic acidosis	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **114** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	5836		HGNC:9725	HUMAN19341
Drosophila melanogaster	33386		FB:FBgn0004507
Rattus norvegicus	64035	10116_1:00261f	RGD:620687	RATNO36304
Caenorhabditis elegans	178777		WB:WBGene00020696
Canis lupus familiaris	403738			CANLF17905
Danio rerio	493916		ZFIN:ZDB-GENE-041205-1
Bos taurus	505472			BOVIN01154
Macaca mulatta	706853			MACMU41758
Pan troglodytes	742309			PANTR08731
Xenopus tropicalis	779523		Xenbase:XB-GENE-478383