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dynein cytoplasmic 2 heavy chain 1

Summary

Gene Symbol

Dync2h1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

110350

PubChem

110350

Alliance of Genome Resources

MGI:107736

Annotation

Keyword

ATP-binding
Alternative splicing
Cell membrane
Cilium
Cilium biogenesis/degradation
Coiled coil
Cytoskeleton
Developmental protein
Dynein
Microtubule
Motor protein
Proteomics identification
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q45VK7	Cytoplasmic dynein 2 heavy chain Dynein cytoplasmic heavy chain 2 Dynein heavy chain 11 Dynein heavy chain isotype 1B
D3Z025

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 22 in total

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GO Term	Evidence Code	PMID
dorsal/ventral pattern formation	IMP	15755804 16061793 16229832
dorsal/ventral pattern formation	IGI	21552265
protein processing	IMP	16061793 16229832
spinal cord motor neuron differentiation	IGI	21552265
central nervous system neuron differentiation	IMP	21552265

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

cilium movement [inference]

cilium movement involved in cell motility

transport along microtubule [inference]

intraciliary transport [inference]

intraciliary retrograde transport

cellular developmental process [inference]

cell differentiation [inference]

cell differentiation in spinal cord [inference]

spinal cord motor neuron differentiation

neuron differentiation

central nervous system neuron differentiation

spinal cord motor neuron differentiation

cellular localization [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

intraciliary transport [inference]

intraciliary retrograde transport

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cilium

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

Golgi organization

cilium organization [inference]

cilium assembly

non-motile cilium assembly

organelle assembly [inference]

cilium assembly

non-motile cilium assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

non-motile cilium assembly

organelle assembly [inference]

cilium assembly

non-motile cilium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

non-motile cilium assembly

plasma membrane bounded cell projection organization [inference]

cilium organization [inference]

cilium assembly

non-motile cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly

non-motile cilium assembly

multicellular organismal process [inference]

pattern specification process [inference]

regionalization [inference]

dorsal/ventral pattern formation

specification of symmetry [inference]

determination of bilateral symmetry [inference]

determination of left/right symmetry

developmental process [inference]

anatomical structure morphogenesis [inference]

appendage morphogenesis [inference]

limb morphogenesis [inference]

embryonic limb morphogenesis

embryonic appendage morphogenesis [inference]

embryonic limb morphogenesis

embryonic morphogenesis [inference]

embryonic appendage morphogenesis [inference]

embryonic limb morphogenesis

anatomical structure development [inference]

blood vessel development [inference]

coronary vasculature development

forebrain development

animal organ development [inference]

cellular developmental process [inference]

cell differentiation [inference]

cell differentiation in spinal cord [inference]

spinal cord motor neuron differentiation

neuron differentiation

central nervous system neuron differentiation

spinal cord motor neuron differentiation

localization [inference]

protein-containing complex localization [inference]

intraciliary transport [inference]

intraciliary retrograde transport

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cilium

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

intraciliary transport [inference]

intraciliary retrograde transport

microtubule-based transport [inference]

transport along microtubule [inference]

intraciliary transport [inference]

intraciliary retrograde transport

establishment of localization in cell [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

intraciliary transport [inference]

intraciliary retrograde transport

cellular localization [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

intraciliary transport [inference]

intraciliary retrograde transport

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cilium

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

positive regulation of smoothened signaling pathway

positive regulation of signal transduction [inference]

positive regulation of smoothened signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of smoothened signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of smoothened signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of smoothened signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of smoothened signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

positive regulation of smoothened signaling pathway

positive regulation of signal transduction [inference]

positive regulation of smoothened signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of smoothened signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

positive regulation of smoothened signaling pathway

positive regulation of signal transduction [inference]

positive regulation of smoothened signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of smoothened signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of smoothened signaling pathway

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
Golgi apparatus	ISO
Golgi apparatus	IEA
cytoplasmic dynein complex	ISM	9373155
cytoplasmic dynein complex	ISO
cytoplasmic dynein complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

dynein complex [inference]

cytoplasmic dynein complex

catalytic complex [inference]

dynein complex [inference]

cytoplasmic dynein complex

cellular anatomical entity [inference]

axoneme

membrane [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium [inference]

motile cilium

9+2 motile cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium [inference]

motile cilium

9+2 motile cilium

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

apical part of cell

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
ATP binding	IEA
minus-end-directed microtubule motor activity	IBA
minus-end-directed microtubule motor activity	IEA
ATP hydrolysis activity	IEA
dynein intermediate chain binding	IBA