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regulator of chromosome condensation 1

Summary

Gene Symbol

RCC1

Organism

Homo sapiens (human)

External Links

NCBI Gene

1104

PubChem

1104

Alliance of Genome Resources

HGNC:1913

Annotation

Keyword

3D-structure
Alternative splicing
Chromosome
Cytoplasm
DNA-binding
Direct protein sequencing
Guanine-nucleotide releasing factor
Methylation
Mitosis
Nucleus
Phosphoprotein
Reference proteome
Repeat

Proteins

Displaying **all 4** entries
UniProt	Protein Name
P18754	Cell cycle regulatory protein Chromosome condensation protein 1
Q5T081
A0A0S2Z404
A0A0S2Z3I4

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
G1/S transition of mitotic cell cycle	IMP	3678831
mitotic spindle organization	IDA	15014043
chromosome segregation	IMP	17435751
mitotic nuclear membrane reassembly	TAS
regulation of mitotic nuclear division	IDA	15014043

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

cell cycle process [inference]

spindle organization [inference]

chromosome segregation

cell cycle phase transition [inference]

mitotic cell cycle phase transition [inference]

G1/S transition of mitotic cell cycle

cell cycle G1/S phase transition [inference]

G1/S transition of mitotic cell cycle

mitotic cell cycle process [inference]

mitotic cell cycle phase transition [inference]

G1/S transition of mitotic cell cycle

mitotic nuclear membrane organization [inference]

mitotic nuclear membrane reassembly

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

cell division

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

spindle assembly

cellular component assembly [inference]

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

spindle assembly

membrane assembly [inference]

nuclear membrane reassembly [inference]

mitotic nuclear membrane reassembly

membrane organization [inference]

membrane assembly [inference]

nuclear membrane reassembly [inference]

mitotic nuclear membrane reassembly

nuclear membrane organization [inference]

nuclear membrane reassembly [inference]

mitotic nuclear membrane reassembly

mitotic nuclear membrane organization [inference]

mitotic nuclear membrane reassembly

viral process

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of microtubule-based process [inference]

regulation of microtubule cytoskeleton organization [inference]

regulation of spindle organization [inference]

regulation of mitotic spindle organization [inference]

regulation of mitotic spindle assembly

regulation of spindle assembly [inference]

regulation of mitotic spindle assembly

regulation of cellular component biogenesis [inference]

regulation of organelle assembly [inference]

regulation of spindle assembly [inference]

regulation of mitotic spindle assembly

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

regulation of cytoskeleton organization [inference]

regulation of microtubule cytoskeleton organization [inference]

regulation of spindle organization [inference]

regulation of mitotic spindle organization [inference]

regulation of mitotic spindle assembly

regulation of spindle assembly [inference]

regulation of mitotic spindle assembly

regulation of nuclear division [inference]

regulation of mitotic nuclear division

regulation of organelle assembly [inference]

regulation of spindle assembly [inference]

regulation of mitotic spindle assembly

regulation of cell cycle [inference]

regulation of mitotic cell cycle

regulation of mitotic nuclear division

regulation of cell cycle process [inference]

regulation of mitotic nuclear division

regulation of spindle organization [inference]

regulation of mitotic spindle organization [inference]

regulation of mitotic spindle assembly

regulation of spindle assembly [inference]

regulation of mitotic spindle assembly

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GO Term	Evidence Code	PMID
chromatin	IDA	12121620 15014043
condensed nuclear chromosome	IDA	15014043
nucleus	IDA	17435751
nucleus	HDA	21630459
nucleoplasm	TAS

GO Hierarchy

cellular component

protein-containing complex

protein-DNA complex [inference]

chromatin

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

chromosome

nuclear chromosome [inference]

condensed nuclear chromosome

condensed chromosome [inference]

condensed nuclear chromosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

chromosome

nuclear chromosome [inference]

condensed nuclear chromosome

condensed chromosome [inference]

condensed nuclear chromosome

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
chromatin binding	IDA	2677018
guanyl-nucleotide exchange factor activity	TAS
guanyl-nucleotide exchange factor activity	IDA	1944575
guanyl-nucleotide exchange factor activity	IMP	11336674
guanyl-nucleotide exchange factor activity	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

GTPase binding [inference]

small GTPase binding

histone binding

protein dimerization activity [inference]

protein heterodimerization activity

ion binding [inference]

anion binding [inference]

sulfate binding

protein-containing complex binding [inference]

chromatin binding

chromatin DNA binding [inference]

nucleosomal DNA binding

nucleosome binding

nucleosomal DNA binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding [inference]

chromatin DNA binding [inference]

nucleosomal DNA binding

sulfur compound binding [inference]

sulfate binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

guanyl-nucleotide exchange factor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Regulator of chromosome condensation

Functional Category

I: Lipid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
cell cycle
cell division

Displaying **all 2** entries
InterPro
Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
Regulator of chromosome condensation, RCC1

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	1104	Xenbase:XB-GENE-979094
Mus musculus	100088		MOUSE40243
Danio rerio	406457		DANRE11018
Bos taurus	534142		BOVIN25050
Rattus norvegicus	682908		RATNO32586
Macaca mulatta	720265		MACMU23578
Monodelphis domestica	100020625		MONDO23313
Equus caballus	100070733		HORSE28984
Ciona intestinalis	100184736		CIOIN09559
Taeniopygia guttata	100230379		TAEGU13720