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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
WD repeat domain 45
Summary
- Gene Symbol
-
- WDR45
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Autophagy
- Cytoplasm
- Disease variant
- Lipid-binding
- Neurodegeneration
- Reference proteome
- Repeat
- WD repeat
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9Y484 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein localization to phagophore assembly site | ||
| autophagy | ||
| autophagy of mitochondrion | ||
| protein lipidation involved in autophagosome assembly | ||
| autophagy of peroxisome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| phagophore assembly site | ||
| phagophore assembly site membrane | ||
| extrinsic component of membrane |
|
|
| cytosol |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| phosphatidylinositol-3,5-bisphosphate binding | ||
| protein kinase binding | ||
| phosphatidylinositol phosphate binding | ||
| phosphatidylinositol-3-phosphate binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Autophagy-related protein
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| nucleophagy |
| phosphatidylinositol-3,5-bisphosphate binding |
| phosphatidylinositol-3-phosphate binding |
| protein localization to phagophore assembly site |
| InterPro |
|---|
| PROPPIN |
| WD40 repeat |
| WD40-repeat-containing domain superfamily |
| WD40/YVTN repeat-like-containing domain superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110739 | neurodegeneration with brain iron accumulation 5 |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 100462757 | PIGXX37307 | |||
| 100565007 | ANOCA15091 | |||
| 100605052 | NOMLE38456 | |||
| 100655767 | LOXAF06543 | |||
| 100705027 | ORENI70091 | |||
| 100734593 | CAVPO23193 | |||
| 100759722 | CRIGR13661 | |||
| 100961269 | OTOGA03709 | |||
| 100985148 | 9597_0:00568a | PANPA41344 | ||
| 100985700 | PANPA41344 |
