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CHM like Rab escort protein

Summary

Gene Symbol

CHML

Organism

Homo sapiens (human)

External Links

NCBI Gene

1122

PubChem

1122

Alliance of Genome Resources

HGNC:1941

Annotation

Keyword

Cytoplasm
GTPase activation
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P26374	Choroideremia-like protein Rab escort protein 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
intracellular protein transport	IEA
small GTPase mediated signal transduction	IEA
vesicle-mediated transport	IBA
protein geranylgeranylation	IDA	15186776
protein geranylgeranylation	IMP	12356470

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein prenylation [inference]

protein geranylgeranylation

cellular metabolic process [inference]

prenylation [inference]

protein prenylation [inference]

protein geranylgeranylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein prenylation [inference]

protein geranylgeranylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein prenylation [inference]

protein geranylgeranylation

macromolecule modification [inference]

protein modification process [inference]

protein prenylation [inference]

protein geranylgeranylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein prenylation [inference]

protein geranylgeranylation

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

small GTPase mediated signal transduction

vesicle-mediated transport

cellular metabolic process [inference]

prenylation [inference]

protein prenylation [inference]

protein geranylgeranylation

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization [inference]

transport [inference]

vesicle-mediated transport

intracellular transport [inference]

intracellular protein transport

organic substance transport [inference]

protein transport [inference]

intracellular protein transport

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

small GTPase mediated signal transduction

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
nucleus	IBA
nucleoplasm	IDA
cytoplasm
cytosol	TAS
cytosol	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

transferase complex [inference]

Rab-protein geranylgeranyltransferase complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 4** entries
GO Term	Evidence Code	PMID
GDP-dissociation inhibitor activity	IEA
GTPase activator activity	IEA
small GTPase binding	IDA	15186776
small GTPase binding	IPI	15186776

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding [inference]

GTPase binding [inference]

small GTPase binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

RAB protein

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
GDP-dissociation inhibitor activity
small GTPase-mediated signal transduction

Displaying **all 2** entries
InterPro
FAD/NAD(P)-binding domain superfamily
GDP dissociation inhibitor

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:2841	asthma	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 30 in total

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Species	Gene ID	Orthologous MAtrix
Gorilla gorilla gorilla	101128760	GORGO17927
Oryzias latipes	101158129	ORYLA04454
Capra hircus	102176250	CAPHI06689
Myotis lucifugus	102426128	MYOLU14506
Erinaceus europaeus	103121997	ERIEU01429
Callorhinchus milii	103177636	CALMI01532
Pteropus vampyrus	105305406	PTEVA16731
Mandrillus leucophaeus	105546747	MANLE27995
Dipodomys ordii	105989649	DIPOR10381
Chinchilla lanigera	106146235	CHILA01402

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements