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farnesyl-diphosphate farnesyltransferase 1

Summary

Gene Symbol

FDFT1

Organism

Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)

External Links

NCBI Gene: 112410702
KEGG Gene ID: nasi:112410702
PubChem: 112410702

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cholesterol biosynthetic process	IEA	30032202
farnesyl diphosphate metabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

farnesyl diphosphate metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

farnesyl diphosphate metabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

farnesyl diphosphate metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

farnesyl diphosphate metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

farnesyl diphosphate metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

farnesyl diphosphate metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

farnesyl diphosphate metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

farnesyl diphosphate metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

farnesyl diphosphate metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

farnesyl diphosphate metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

farnesyl diphosphate metabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

farnesyl diphosphate metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

farnesyl diphosphate metabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
squalene synthase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring alkyl or aryl (other than methyl) groups [inference]

prenyltransferase activity [inference]

farnesyltranstransferase activity [inference]

squalene synthase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Cetacea

Group Name

Trans-isoprenyl diphosphate synthases, eukaryotic-type

Functional Category

D: Cell cycle control, cell division, chromosome partitioning
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
catalytic activity
cholesterol biosynthetic process
ergosterol biosynthetic process
farnesyl diphosphate metabolic process
farnesyl-diphosphate farnesyltransferase activity
farnesyltranstransferase activity
lipid biosynthetic process
squalene synthase activity
transferase activity

Displaying **all 5** entries
InterPro
Isoprenoid synthase domain superfamily
Squalene synthase-like
Squalene/phytoene synthase, conserved site
Squalene/phytoene synthase
Trans-isoprenyl diphosphate synthases, eukaryotic-type

KEGG BRITE Database

Orthology

K00801

Name

farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]

References

Ortholog

Displaying entries **1 - 10** of 12 in total

1

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Next ›

Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Orcinus orca	101283685	9733_0:00190d
Tursiops truncatus	101331125	9739_0:0018b9
Physeter catodon	102983337	9755_0:0047e4
Balaenoptera acutorostrata	102999512	9767_0:001c98
Lipotes vexillifer	103090735	118797_0:0043dd
Delphinapterus leucas	111185363	9749_0:00016c
Lagenorhynchus obliquidens	113610109	90247_0:003895
Monodon monoceros	114884552	40151_0:003804
Globicephala melas	115864963	9731_0:002c3a
Phocoena sinus	116754942	42100_1:001994

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024