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sphingomyelin phosphodiesterase 4

Summary

Gene Symbol

SMPD4

Organism

Apteryx rowi (Okarito brown kiwi)

External Links

NCBI Gene: 112970546
KEGG Gene ID: arow:112970546
PubChem: 112970546

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
glycerophospholipid catabolic process	IEA	30032202
ceramide biosynthetic process	IEA	30032202
sphingomyelin catabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

amide metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingomyelin metabolic process [inference]

sphingomyelin catabolic process

amide biosynthetic process [inference]

ceramide biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingomyelin metabolic process [inference]

sphingomyelin catabolic process

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

sphingomyelin metabolic process [inference]

sphingomyelin catabolic process

phospholipid catabolic process [inference]

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

sphingomyelin metabolic process [inference]

sphingomyelin catabolic process

phospholipid catabolic process [inference]

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingomyelin metabolic process [inference]

sphingomyelin catabolic process

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

sphingomyelin metabolic process [inference]

sphingomyelin catabolic process

phospholipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingomyelin metabolic process [inference]

sphingomyelin catabolic process

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

sphingomyelin metabolic process [inference]

sphingomyelin catabolic process

phospholipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingomyelin metabolic process [inference]

sphingomyelin catabolic process

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

sphingomyelin metabolic process [inference]

sphingomyelin catabolic process

phospholipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

sphingomyelin metabolic process [inference]

sphingomyelin catabolic process

phospholipid catabolic process [inference]

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingomyelin metabolic process [inference]

sphingomyelin catabolic process

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

sphingomyelin metabolic process [inference]

sphingomyelin catabolic process

phospholipid catabolic process [inference]

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

sphingomyelin metabolic process [inference]

sphingomyelin catabolic process

phospholipid catabolic process [inference]

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingomyelin metabolic process [inference]

sphingomyelin catabolic process

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

sphingomyelin metabolic process [inference]

sphingomyelin catabolic process

phospholipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
sphingomyelin phosphodiesterase D activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

lipase activity [inference]

phospholipase activity [inference]

sphingomyelin phosphodiesterase D activity

phosphoric ester hydrolase activity [inference]

phosphoric diester hydrolase activity [inference]

sphingomyelin phosphodiesterase D activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Magnesium transporter

Functional Category

O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
magnesium ion transmembrane transporter activity
monoatomic ion transport

Displaying 1 entry
InterPro
Magnesium transporter MRS2-like

KEGG BRITE Database

Orthology

K12353

Name

sphingomyelin phosphodiesterase 4 [EC:3.1.4.12]

References

16517606

Ortholog

Displaying entries **11 - 20** of 72 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Columba livia	102086716	8932_0:001368
Calypte anna	103536671	9244_0:0027f3
Manacus vitellinus	103762898	328815_0:002853
Merops nubicus	103770854	57421_0:001694
Acanthisitta chloris	103808465	57068_0:0033fb
Serinus canaria	103818007	9135_0:00291f
Aptenodytes forsteri	103899535	9233_0:001f5f
Pygoscelis adeliae	103922674	9238_0:002e5e
Nipponia nippon	104011484	128390_0:0015ce
Pelecanus crispus	104038024	36300_0:0006ce

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Last updated: December 9, 2024