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transient receptor potential cation channel, subfamily V, member 6

Summary

Gene Symbol

Trpv6

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

114246

PubChem

114246

Alliance of Genome Resources

RGD:69335

Annotation

Keyword

3D-structure
ANK repeat
Calcium channel
Calmodulin-binding
Cell membrane
Glycoprotein
Ion channel
Metal-binding
Phosphoprotein
Receptor
Reference proteome
Repeat
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B6ZDS2
Q9R186	Calcium transport protein 1 Epithelial calcium channel 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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2

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GO Term	Evidence Code	PMID
protein homotetramerization	IPI	27296226
response to calcium ion	IEA ISO ISS
calcium ion homeostasis	IEA ISO ISS
parathyroid hormone secretion	IEA ISO
calcium ion import across plasma membrane	IBA IEA IMP ISO ISS	10428857

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

export from cell [inference]

secretion by cell [inference]

signal release [inference]

hormone secretion [inference]

endocrine hormone secretion [inference]

parathyroid hormone secretion

homeostatic process [inference]

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

monoatomic cation homeostasis [inference]

calcium ion homeostasis

inorganic ion homeostasis [inference]

calcium ion homeostasis

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to calcium ion

response to inorganic substance [inference]

response to metal ion [inference]

response to calcium ion

response to oxygen-containing compound [inference]

response to calcium ion

response to salt [inference]

response to calcium ion

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport

calcium ion import

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

hormone transport [inference]

hormone secretion [inference]

endocrine hormone secretion [inference]

parathyroid hormone secretion

secretion [inference]

secretion by cell [inference]

signal release [inference]

hormone secretion [inference]

endocrine hormone secretion [inference]

parathyroid hormone secretion

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

organic substance transport [inference]

calcium ion transport

calcium ion import

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

export from cell [inference]

secretion by cell [inference]

signal release [inference]

hormone secretion [inference]

endocrine hormone secretion [inference]

parathyroid hormone secretion

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone transport [inference]

hormone secretion [inference]

endocrine hormone secretion [inference]

parathyroid hormone secretion

Displaying **all 3** entries
GO Term	Evidence Code	PMID
apical plasma membrane	IC	10875938
plasma membrane	IBA IEA ISO ISS
calcium channel complex	IEA ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

calcium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

calcium channel complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
calcium-activated cation channel activity	TAS	12138163
metal ion binding	IEA
identical protein binding	IEA IPI ISO	27296226
calmodulin binding	IEA ISO ISS
calcium channel activity	IBA IDA IEA ISO	10428857 10875938 27296226

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity

ligand-gated monoatomic cation channel activity [inference]

calcium-activated cation channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

calcium-activated cation channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity

ligand-gated monoatomic cation channel activity [inference]

calcium-activated cation channel activity

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity

ligand-gated monoatomic cation channel activity [inference]

calcium-activated cation channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

calcium-activated cation channel activity

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

calcium-activated cation channel activity

monoatomic ion-gated channel activity [inference]

calcium-activated cation channel activity

salt transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

binding [inference]

protein binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **71 - 77** of 77 in total

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Species	Gene ID	Orthologous MAtrix
Salarias fasciatus	115396975	SALFA30134
Sparus aurata	115567242	SPAAU58930
Rhinolophus ferrumequinum	117018108	RHIFE11884
Scophthalmus maximus	118314819	SCOMX15984
Canis lupus familiaris	119874628	CANLF04443
Panthera leo	122212922	PANLE22768
Ursus americanus	123788847	URSAM14442