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acrosin prepropeptide

Summary

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

11434

PubChem

11434

Alliance of Genome Resources

MGI:87884

Annotation

Keyword

Disulfide bond
Glycoprotein
Reference proteome
Serine protease
Signal
Zymogen

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3ZB05
P23578

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
acrosome matrix dispersal	ISO
acrosome matrix dispersal	IEA
activation of adenylate cyclase activity	ISS
activation of adenylate cyclase activity	ISO
single fertilization	IMP	15685642

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

acrosome matrix dispersal

protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

acrosome matrix dispersal

protein catabolic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

acrosome matrix dispersal

protein catabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

acrosome matrix dispersal

protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process

cellular process [inference]

cell recognition [inference]

cell-cell recognition [inference]

sperm-egg recognition [inference]

binding of sperm to zona pellucida

reproductive process [inference]

fertilization [inference]

single fertilization

sperm-egg recognition [inference]

binding of sperm to zona pellucida

multicellular organismal reproductive process [inference]

penetration of zona pellucida

multicellular organismal process [inference]

multi-multicellular organism process [inference]

penetration of zona pellucida

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

response to steroid hormone

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to steroid hormone

response to organic cyclic compound [inference]

response to steroid hormone

response to lipid [inference]

response to steroid hormone

biological regulation [inference]

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of cyclase activity [inference]

positive regulation of adenylate cyclase activity [inference]

activation of adenylate cyclase activity

positive regulation of lyase activity [inference]

positive regulation of adenylate cyclase activity [inference]

activation of adenylate cyclase activity

regulation of catalytic activity [inference]

regulation of cyclase activity [inference]

positive regulation of cyclase activity [inference]

positive regulation of adenylate cyclase activity [inference]

activation of adenylate cyclase activity

regulation of adenylate cyclase activity [inference]

positive regulation of adenylate cyclase activity [inference]

activation of adenylate cyclase activity

positive regulation of catalytic activity [inference]

positive regulation of cyclase activity [inference]

positive regulation of adenylate cyclase activity [inference]

activation of adenylate cyclase activity

positive regulation of lyase activity [inference]

positive regulation of adenylate cyclase activity [inference]

activation of adenylate cyclase activity

regulation of lyase activity [inference]

regulation of adenylate cyclase activity [inference]

positive regulation of adenylate cyclase activity [inference]

activation of adenylate cyclase activity

positive regulation of lyase activity [inference]

positive regulation of adenylate cyclase activity [inference]

activation of adenylate cyclase activity

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
acrosomal vesicle	ISO
acrosomal vesicle	IDA	7798216
Golgi-associated vesicle	ISO
Golgi-associated vesicle	IEA
protein-containing complex	ISO

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

acrosomal matrix

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

Golgi-associated vesicle

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

Golgi-associated vesicle

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

Golgi-associated vesicle

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
amidase activity	ISS
serine-type endopeptidase activity	ISS
serine-type endopeptidase activity	ISO
serine-type endopeptidase activity	TAS	12398221
serine-type endopeptidase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity

endopeptidase activity [inference]

serine-type endopeptidase activity

serine-type peptidase activity

serine-type endopeptidase activity

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [inference]

amidase activity

serine hydrolase activity [inference]

serine-type peptidase activity

serine-type endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity

endopeptidase activity [inference]

serine-type endopeptidase activity

serine-type peptidase activity

serine-type endopeptidase activity

binding [inference]

protein binding

carbohydrate binding [inference]

monosaccharide binding [inference]

small molecule binding [inference]

monosaccharide binding [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

isoform A

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
proteolysis
serine-type endopeptidase activity

Displaying **all 6** entries
InterPro
Peptidase S1, PA clan, chymotrypsin-like fold
Peptidase S1, PA clan
Peptidase S1A, chymotrypsin family
Serine proteases, trypsin domain
Serine proteases, trypsin family, histidine active site
Serine proteases, trypsin family, serine active site

Ortholog

Displaying **all 10** entries
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	49	Xenbase:XB-GENE-5723327
Xenopus tropicalis	11434	Xenbase:XB-GENE-5892360
Rattus norvegicus	24163	Xenbase:XB-GENE-5892360	RATNO37200
Danio rerio	75002	ZFIN:ZDB-GENE-090313-370
Danio rerio	283471	ZFIN:ZDB-GENE-090313-370
Cavia porcellus	100717414		CAVPO24474
Cricetulus griseus	100754856		CRIGR24988
Octodon degus	101581357		OCTDE21277
Monodelphis domestica	103093639		MONDO00414
Phascolarctos cinereus	110201632		PHACI13597