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SLIT and NTRK like family member 1

Summary

Gene Symbol

SLITRK1

Organism

Homo sapiens (human)

External Links

NCBI Gene

114798

PubChem

114798

Alliance of Genome Resources

HGNC:20297

JoGo

SLITRK1

TogoVar

SLITRK1

Annotation

Keyword

3D-structure
Glycoprotein
Leucine-rich repeat
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Secreted
Signal
Synapse
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q96PX8	Leucine-rich repeat-containing protein 12

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
endocytosis	IEA
axonogenesis	IBA
synapse assembly	IMP	27273464
gene expression	IEA
adult behavior	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic cyclic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic hydroxy compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

synaptic membrane adhesion

cell growth [inference]

developmental cell growth [inference]

neuron projection extension

vesicle-mediated transport [inference]

endocytosis

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

synapse assembly

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis

cell junction organization [inference]

cell junction assembly [inference]

synapse assembly

synapse organization [inference]

synapse assembly

multicellular organismal process [inference]

behavior [inference]

multicellular organism growth

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis

growth [inference]

cell growth [inference]

developmental cell growth [inference]

neuron projection extension

developmental growth [inference]

multicellular organism growth

developmental cell growth [inference]

neuron projection extension

developmental growth involved in morphogenesis [inference]

neuron projection extension

homeostatic process

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis

import into cell [inference]

endocytosis

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of synapse assembly

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of synapse assembly

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of axonogenesis [inference]

positive regulation of axonogenesis

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of synapse assembly

regulation of cellular process [inference]

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

regulation of axonogenesis [inference]

positive regulation of axonogenesis

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

regulation of presynapse organization [inference]

regulation of presynapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of synapse assembly

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
extracellular region	IEA
plasma membrane	TAS
synapse	ISS
postsynaptic density membrane	IBA
glutamatergic synapse	IDA	23345436

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction [inference]

synapse

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	19640509 32296183

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

SLIT and NTRK like family member 1

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 2** entries
Gene Ontology
positive regulation of synapse assembly
regulation of presynapse assembly

Displaying **all 5** entries
InterPro
Cysteine-rich flanking region, C-terminal
Leucine-rich repeat domain superfamily
Leucine-rich repeat, typical subtype
Leucine-rich repeat
Slitrk family

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0050587	trichotillomania	Alliance of Genome Resources
DOID:11119	Gilles de la Tourette syndrome	Alliance of Genome Resources

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

GlyTouCan

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UniCarb-DR

LM-GlycoRepo

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Tools

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements