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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
ADAM metallopeptidase domain 12
Summary
- Gene Symbol
-
- Adam12
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cell adhesion
- Cleavage on pair of basic residues
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Metal-binding
- Metalloprotease
- Phosphoprotein
- Reference proteome
- SH3-binding
- Signal
- Transmembrane helix
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q61824 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| positive regulation of angiogenesis | ||
| cell adhesion |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| nucleoplasm |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| SH3 domain binding | ||
| metal ion binding | ||
| metalloendopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- disintegrin and metalloproteinase domain-containing protein 12
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:8398 | osteoarthritis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 8038 | HGNC:190 | HUMAN03363 | ||
| 181489 | WB:WBGene00000074 | |||
| 450818 | PANTR01789 | |||
| 563275 | ZFIN:ZDB-GENE-070809-1 | DANRE12891 | ||
| 677729 | Xenbase:XB-GENE-982139 | |||
| 679837 | RGD:1583652 | RATNO20459 | ||
| 696405 | MACMU45741 | |||
| 3772109 | FB:FBgn0265140 | |||
| 100013486 | MONDO07423 | |||
| 100056196 | HORSE15530 |
