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ADAM metallopeptidase domain 9

Summary

Gene Symbol

Adam9

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

11502

PubChem

11502

Alliance of Genome Resources

MGI:105376

Annotation

Keyword

Cell membrane
Direct protein sequencing
Disulfide bond
EGF-like domain
Glycoprotein
Metal-binding
Metalloprotease
Phosphoprotein
Proteomics identification
Reference proteome
Signal
Transmembrane helix
Zinc
Zymogen

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q61072	Meltrin-gamma Metalloprotease/disintegrin/cysteine-rich protein 9 Myeloma cell metalloproteinase
Q3U1W3
Q3UG15
A0A140LHU0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 33 in total

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GO Term	Evidence Code	PMID
proteolysis
membrane protein ectodomain proteolysis	ISO
membrane protein ectodomain proteolysis	IDA	19273593 22480688
membrane protein ectodomain proteolysis	IBA
cell adhesion	ISO

GO Hierarchy

biological process

immune system process [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

monocyte activation

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

membrane protein proteolysis [inference]

amyloid precursor protein metabolic process [inference]

amyloid precursor protein catabolic process

protein maturation [inference]

protein processing

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

membrane protein proteolysis [inference]

amyloid precursor protein metabolic process [inference]

amyloid precursor protein catabolic process

protein maturation [inference]

protein processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

membrane protein proteolysis [inference]

amyloid precursor protein metabolic process [inference]

amyloid precursor protein catabolic process

protein maturation [inference]

protein processing

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

membrane protein proteolysis [inference]

amyloid precursor protein metabolic process [inference]

amyloid precursor protein catabolic process

protein maturation [inference]

protein processing

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

monocyte activation

cell adhesion

cell-substrate adhesion [inference]

cell-matrix adhesion

cell adhesion mediated by integrin

cell-cell adhesion mediated by integrin

cell-cell adhesion [inference]

cell-cell adhesion mediated by integrin

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

epidermal cell differentiation [inference]

keratinocyte differentiation

cell motility [inference]

cell migration

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

monocyte activation

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

epidermal cell differentiation [inference]

keratinocyte differentiation

response to stimulus [inference]

response to stress [inference]

response to oxidative stress [inference]

response to reactive oxygen species [inference]

response to hydrogen peroxide

response to fluid shear stress [inference]

response to laminar fluid shear stress

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to endogenous stimulus [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to chemical [inference]

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to organic cyclic compound [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to lipid [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

cellular response to lipid [inference]

cellular response to lipopolysaccharide

response to cytokine [inference]

response to tumor necrosis factor

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

response to inorganic substance [inference]

response to metal ion [inference]

response to hydrogen peroxide

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

response to antineoplastic agent

response to oxygen-containing compound [inference]

response to reactive oxygen species [inference]

response to hydrogen peroxide

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

response to calcium ion

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

response to salt [inference]

response to calcium ion

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of cellular catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of cellular catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of keratinocyte migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of epithelial cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of keratinocyte migration

regulation of keratinocyte migration [inference]

positive regulation of keratinocyte migration

positive regulation of cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of keratinocyte migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of keratinocyte migration

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of keratinocyte migration

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of cell adhesion [inference]

positive regulation of cell adhesion mediated by integrin

positive regulation of cellular component organization [inference]

positive regulation of syncytium formation by plasma membrane fusion [inference]

positive regulation of macrophage fusion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of keratinocyte migration

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of developmental process [inference]

positive regulation of syncytium formation by plasma membrane fusion [inference]

positive regulation of macrophage fusion

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

regulation of developmental process [inference]

positive regulation of developmental process [inference]

positive regulation of syncytium formation by plasma membrane fusion [inference]

positive regulation of macrophage fusion

regulation of syncytium formation by plasma membrane fusion [inference]

regulation of macrophage fusion [inference]

positive regulation of macrophage fusion

positive regulation of syncytium formation by plasma membrane fusion [inference]

positive regulation of macrophage fusion

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

regulation of cell adhesion [inference]

regulation of cell adhesion mediated by integrin [inference]

positive regulation of cell adhesion mediated by integrin

positive regulation of cell adhesion [inference]

positive regulation of cell adhesion mediated by integrin

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of cellular catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis [inference]

positive regulation of membrane protein ectodomain proteolysis

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of cellular catabolic process [inference]

positive regulation of membrane protein ectodomain proteolysis

positive regulation of cell adhesion [inference]

positive regulation of cell adhesion mediated by integrin

positive regulation of cellular component organization [inference]

positive regulation of syncytium formation by plasma membrane fusion [inference]

positive regulation of macrophage fusion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of keratinocyte migration

regulation of cellular component organization [inference]

positive regulation of cellular component organization [inference]

positive regulation of syncytium formation by plasma membrane fusion [inference]

positive regulation of macrophage fusion

regulation of syncytium formation by plasma membrane fusion [inference]

regulation of macrophage fusion [inference]

positive regulation of macrophage fusion

positive regulation of syncytium formation by plasma membrane fusion [inference]

positive regulation of macrophage fusion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of epithelial cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of keratinocyte migration

regulation of keratinocyte migration [inference]

positive regulation of keratinocyte migration

positive regulation of cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of keratinocyte migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of keratinocyte migration

regulation of multicellular organismal process [inference]

regulation of epithelial cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of keratinocyte migration

regulation of keratinocyte migration [inference]

positive regulation of keratinocyte migration

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
extracellular space	ISO
extracellular space	IMP	9920899
extracellular space	IBA
extracellular space	HDA	24006456
cytoplasm	IDA	15739225

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

plasma membrane region [inference]

basolateral plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
metalloendopeptidase activity	ISO
metalloendopeptidase activity	IDA	22480688
metalloendopeptidase activity	IBA
protein kinase C binding	IPI	9857183
integrin binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metalloendopeptidase activity involved in amyloid precursor protein catabolic process

metallopeptidase activity

metalloendopeptidase activity

metalloendopeptidase activity involved in amyloid precursor protein catabolic process

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metalloendopeptidase activity involved in amyloid precursor protein catabolic process

metallopeptidase activity

metalloendopeptidase activity

metalloendopeptidase activity involved in amyloid precursor protein catabolic process

binding [inference]

protein binding

signaling receptor binding [inference]

integrin binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein kinase C binding

protein domain specific binding [inference]

SH3 domain binding

laminin binding

cell adhesion molecule binding [inference]

integrin binding

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

extracellular matrix binding [inference]

laminin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Disintegrin

Functional Category

M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
metal ion binding
metalloendopeptidase activity
metallopeptidase activity
proteolysis

Displaying **all 8** entries
InterPro
ADAM, cysteine-rich domain
Disintegrin domain superfamily
Disintegrin domain
EGF-like domain
Metallopeptidase, catalytic domain superfamily
Peptidase M12B, ADAM/reprolysin
Peptidase M12B, propeptide
Reprolysin domain, adamalysin-type

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0111020	cone-rod dystrophy 9	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements