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alcohol dehydrogenase 1 (class I)

Summary

Gene Symbol

Adh1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

11522

PubChem

11522

Alliance of Genome Resources

MGI:87921

Annotation

Keyword

Acetylation
Cytoplasm
Metal-binding
NAD
Oxidoreductase
Reference proteome
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P00329	ADH-A2 Alcohol dehydrogenase A subunit
Q3UKA4	Alcohol dehydrogenase A subunit

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
retinoid metabolic process	IMP	12027900
ethanol catabolic process	IDA	518534
ethanol catabolic process	IMP	10358022
lipid metabolic process	ISO
animal organ regeneration	IEA

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

small molecule catabolic process [inference]

alcohol catabolic process [inference]

primary alcohol catabolic process [inference]

ethanol catabolic process

organic substance catabolic process [inference]

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

primary alcohol catabolic process [inference]

ethanol catabolic process

hormone metabolic process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

retinoic acid metabolic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

primary metabolic process [inference]

lipid metabolic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

ethanol metabolic process [inference]

ethanol catabolic process

primary alcohol catabolic process [inference]

ethanol catabolic process

retinol metabolic process

alcohol catabolic process [inference]

primary alcohol catabolic process [inference]

ethanol catabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

retinoic acid metabolic process

small molecule catabolic process [inference]

alcohol catabolic process [inference]

primary alcohol catabolic process [inference]

ethanol catabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

retinoic acid metabolic process

lipid metabolic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

olefinic compound metabolic process [inference]

retinol metabolic process

organic substance catabolic process [inference]

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

primary alcohol catabolic process [inference]

ethanol catabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

ethanol metabolic process [inference]

ethanol catabolic process

primary alcohol catabolic process [inference]

ethanol catabolic process

retinol metabolic process

alcohol catabolic process [inference]

primary alcohol catabolic process [inference]

ethanol catabolic process

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

primary alcohol catabolic process [inference]

ethanol catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

retinoic acid metabolic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

multicellular organismal process [inference]

behavior [inference]

adult behavior [inference]

behavioral response to ethanol

developmental process [inference]

anatomical structure development [inference]

regeneration [inference]

animal organ regeneration

animal organ development [inference]

animal organ regeneration

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

response to steroid hormone

response to progesterone

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to steroid hormone

response to progesterone

response to organic cyclic compound [inference]

response to testosterone

response to steroid hormone

response to progesterone

response to lipid [inference]

response to steroid hormone

response to progesterone

response to ketone [inference]

response to oxygen-containing compound [inference]

response to retinoic acid

response to ketone [inference]

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
intracellular anatomical structure	IDA	9002638
nucleoplasm	ISO
mitochondrion	IDA	3996732
cytosol	ISO
cytosol	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
alcohol dehydrogenase (NAD+) activity	ISO
alcohol dehydrogenase (NAD+) activity	TAS	12027900
alcohol dehydrogenase (NAD+) activity	IDA	3996732 518534 6370228 6816803 7026729
NAD-retinol dehydrogenase activity	ISO
NAD-retinol dehydrogenase activity	IGI	15193143

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

NAD-retinol dehydrogenase activity

alcohol dehydrogenase [NAD(P)+] activity [inference]

alcohol dehydrogenase (NAD+) activity

binding [inference]

protein binding [inference]

identical protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

organic cyclic compound binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Dehydrogenase

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
S-(hydroxymethyl)glutathione dehydrogenase activity
alcohol dehydrogenase activity, zinc-dependent
ethanol oxidation
formaldehyde catabolic process
metal ion binding
oxidoreductase activity
zinc ion binding

Displaying **all 6** entries
InterPro
Alcohol dehydrogenase class III
Alcohol dehydrogenase, zinc-type, conserved site
Alcohol dehydrogenase-like, C-terminal
Alcohol dehydrogenase-like, N-terminal
GroES-like superfamily
NAD(P)-binding domain superfamily

Ortholog

Displaying entries **1 - 10** of 89 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	124	Xenbase:XB-GENE-6041030	HUMAN76694
Homo sapiens	125	Xenbase:XB-GENE-6041030	HUMAN76695
Homo sapiens	126	Xenbase:XB-GENE-5955954	HUMAN76699
Danio rerio	127	ZFIN:ZDB-GENE-040426-1910
Saccharomyces cerevisiae S288C	128	SGD:S000002327
Xenopus tropicalis	130	Xenbase:XB-GENE-6041030
Xenopus tropicalis	131	Xenbase:XB-GENE-6041030
Xenopus tropicalis	11522	Xenbase:XB-GENE-6041030
Xenopus tropicalis	11529	Xenbase:XB-GENE-6041030
Rattus norvegicus	24172		RATNO25376