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alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

Summary

Gene Symbol

Adh7

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

11529

PubChem

11529

Alliance of Genome Resources

MGI:87926

Annotation

Keyword

Cytoplasm
Lipid metabolism
Metal-binding
NAD
Oxidoreductase
Reference proteome
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q64437	ADH-C2 Alcohol dehydrogenase 7 Alcohol dehydrogenase class 4 mu/sigma chain Alcohol dehydrogenase class IV mu/sigma chain Gastric alcohol dehydrogenase Omega-hydroxydecanoate dehydrogenase ADH7 Retinol dehydrogenase
Q9D748

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 8** of 8 in total

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GO Term	Evidence Code	PMID
retinol metabolic process	IBA IMP ISO	10358022 10402668
retinoic acid metabolic process	IBA IMP	10358022 10402668
ethanol catabolic process	IMP	10358022

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

small molecule catabolic process [inference]

alcohol catabolic process [inference]

primary alcohol catabolic process [inference]

ethanol catabolic process

organic substance catabolic process [inference]

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

primary alcohol catabolic process [inference]

ethanol catabolic process

hormone metabolic process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

retinoic acid metabolic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

small molecule metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

ethanol metabolic process

ethanol catabolic process

primary alcohol catabolic process [inference]

ethanol catabolic process

retinol metabolic process

alcohol catabolic process [inference]

primary alcohol catabolic process [inference]

ethanol catabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

retinoic acid metabolic process

small molecule catabolic process [inference]

alcohol catabolic process [inference]

primary alcohol catabolic process [inference]

ethanol catabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

retinoic acid metabolic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

olefinic compound metabolic process [inference]

retinol metabolic process

organic substance catabolic process [inference]

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

primary alcohol catabolic process [inference]

ethanol catabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

ethanol metabolic process

ethanol catabolic process

primary alcohol catabolic process [inference]

ethanol catabolic process

retinol metabolic process

alcohol catabolic process [inference]

primary alcohol catabolic process [inference]

ethanol catabolic process

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

primary alcohol catabolic process [inference]

ethanol catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

retinoic acid metabolic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid omega-oxidation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

response to chemical [inference]

response to organic substance [inference]

response to alcohol [inference]

response to ethanol

response to oxygen-containing compound [inference]

response to alcohol [inference]

response to ethanol

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
intracellular anatomical structure	IDA	9002638
plasma membrane	IEA ISO
cytosol	IBA IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying entries **6 - 10** of 12 in total

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GO Term	Evidence Code	PMID
retinol binding	ISO
NAD-retinol dehydrogenase activity	IBA IDA ISO ISS	3663136
identical protein binding	ISO
aldehyde oxidase activity	ISO
alcohol dehydrogenase (NAD+) activity	IBA IDA ISO TAS	12027900 518534 6372555 7026729

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

NAD-retinol dehydrogenase activity

alcohol dehydrogenase [NAD(P)+] activity [inference]

alcohol dehydrogenase (NAD+) activity

alcohol dehydrogenase activity, zinc-dependent

omega-hydroxydecanoate dehydrogenase activity

oxidoreductase activity, acting on the aldehyde or oxo group of donors [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor [inference]

aldehyde oxidase activity

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

receptor antagonist activity

identical protein binding

lipid binding [inference]

isoprenoid binding [inference]

retinoid binding [inference]

retinol binding

small molecule binding [inference]

vitamin binding [inference]

retinol binding

alcohol binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor inhibitor activity [inference]

receptor antagonist activity

molecular function inhibitor activity [inference]

signaling receptor inhibitor activity [inference]

receptor antagonist activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

alcohol dehydrogenase class 4 mu/sigma chain

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
NAD-retinol dehydrogenase activity
alcohol dehydrogenase activity, zinc-dependent
ethanol oxidation
metal ion binding
oxidoreductase activity
retinoic acid metabolic process
retinol metabolic process
small molecule metabolic process
zinc ion binding

Displaying **all 5** entries
InterPro
Alcohol dehydrogenase, zinc-type, conserved site
Alcohol dehydrogenase-like, C-terminal
Alcohol dehydrogenase-like, N-terminal
GroES-like superfamily
NAD(P)-binding domain superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:14330	Parkinson's disease	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 79 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	131		HGNC:256	HUMAN76702
Drosophila melanogaster	41311		FB:FBgn0011768
Rattus norvegicus	171178	10116_1:000e45	RGD:621638
Caenorhabditis elegans	178597		WB:WBGene00019240
Danio rerio	322482		ZFIN:ZDB-GENE-030529-3
Danio rerio	393427		ZFIN:ZDB-GENE-040426-1165
Danio rerio	402841		ZFIN:ZDB-GENE-030529-2
Danio rerio	402939		ZFIN:ZDB-GENE-040426-1910
Xenopus tropicalis	496916		Xenbase:XB-GENE-5732839
Xenopus tropicalis	594969		Xenbase:XB-GENE-6041030