GlyCosmos Portal

Submissions

Rho GTPase activating protein 33

Summary

Gene Symbol

ARHGAP33

Organism

Homo sapiens (human)

External Links

NCBI Gene

115703

PubChem

115703

Alliance of Genome Resources

HGNC:23085

Annotation

Keyword

Alternative splicing
GTPase activation
Methylation
Phosphoprotein
Protein transport
Reference proteome
SH3 domain

Proteins

Displaying **all 2** entries
UniProt	Protein Name
O14559	Rho-type GTPase-activating protein 33 Sorting nexin-26 Tc10/CDC42 GTPase-activating protein
A1A5D2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
small GTPase mediated signal transduction	IBA
response to toxic substance	IEA
protein transport	IEA
regulation of dendritic spine morphogenesis	IEA
regulation of postsynapse assembly	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

small GTPase mediated signal transduction

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

response to stimulus [inference]

response to chemical [inference]

response to toxic substance

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

protein transport

nitrogen compound transport [inference]

protein transport

establishment of protein localization [inference]

protein transport

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of dendritic spine morphogenesis

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

small GTPase mediated signal transduction

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of postsynapse assembly

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

regulation of dendritic spine morphogenesis

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

regulation of postsynapse assembly

regulation of postsynapse organization [inference]

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of postsynapse assembly

Displaying entries **1 - 5** of 11 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
fibrillar center	IBA
nucleoplasm	IBA
Golgi apparatus	IBA
cytosol	TAS
plasma membrane	IBA

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

cytoplasm [inference]

cell cortex

cytosol

membrane [inference]

plasma membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

neuron spine [inference]

dendritic spine

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

postsynaptic specialization [inference]

postsynaptic density

postsynapse [inference]

dendritic spine

Displaying **all 4** entries
GO Term	Evidence Code	PMID
GTPase activator activity	IBA
protein binding	IPI	16777849
protein kinase binding	IPI	20873783
phosphatidylinositol binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

rho GTPase-activating protein 33

Functional Category

I: Lipid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
phosphatidylinositol binding
small GTPase-mediated signal transduction

Displaying **all 5** entries
InterPro
PX domain superfamily
Rho GTPase activation protein
Rho GTPase-activating protein domain
SH3 domain
SH3-like domain superfamily

Ortholog

Displaying entries **1 - 10** of 38 in total

1

2

3

4

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	9743	FB:FBgn0032821
Caenorhabditis elegans	12549	WB:WBGene00009800
Caenorhabditis elegans	57514	WB:WBGene00009800
Xenopus tropicalis	115703	Xenbase:XB-GENE-852586
Drosophila melanogaster	226652	FB:FBgn0032821
Mus musculus	233071		MOUSE55146
Drosophila melanogaster	257106	FB:FBgn0032821
Drosophila melanogaster	330914	FB:FBgn0032821
Macaca mulatta	710938		MACMU17978
Pan troglodytes	748029		PANTR18039