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aldo-keto reductase family 1 member B

Summary

Gene Symbol

Akr1b1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

11677

PubChem

11677

Alliance of Genome Resources

MGI:1353494

Annotation

Keyword

Acetylation
Cytoplasm
Direct protein sequencing
Lipid metabolism
NADP
Oxidoreductase
Phosphoprotein
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P45376	Aldehyde reductase Aldo-keto reductase family 1 member B3 Aldose reductase
Q3UDY1	Aldose reductase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	PMID
retinoid metabolic process	ISS
retinoid metabolic process	ISO
tissue homeostasis	ISO
epithelial cell maturation	IMP	16449351
renal water homeostasis	IMP	16449351

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid biosynthetic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic cyclic compound biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

secondary metabolic process [inference]

polyketide metabolic process [inference]

hormone metabolic process [inference]

retinol metabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

unsaturated fatty acid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

cellular ketone metabolic process [inference]

quinone metabolic process [inference]

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

unsaturated fatty acid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

retinol metabolic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

lactone metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process

hexose metabolic process [inference]

fructose metabolic process [inference]

fructose biosynthetic process

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid biosynthetic process

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid biosynthetic process

alditol metabolic process [inference]

hexitol metabolic process [inference]

sorbitol metabolic process [inference]

sorbitol biosynthetic process

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

unsaturated fatty acid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

retinol metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process

hexose metabolic process [inference]

fructose metabolic process [inference]

fructose biosynthetic process

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid biosynthetic process

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

hexitol metabolic process [inference]

sorbitol metabolic process [inference]

sorbitol biosynthetic process

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

primary alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

tertiary alcohol metabolic process [inference]

doxorubicin metabolic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

unsaturated fatty acid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular ketone metabolic process [inference]

quinone metabolic process [inference]

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process

hexose metabolic process [inference]

fructose metabolic process [inference]

fructose biosynthetic process

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid biosynthetic process

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid biosynthetic process

alditol metabolic process [inference]

hexitol metabolic process [inference]

sorbitol metabolic process [inference]

sorbitol biosynthetic process

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

unsaturated fatty acid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

unsaturated fatty acid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

retinol metabolic process

polyketide metabolic process [inference]

cellular ketone metabolic process [inference]

quinone metabolic process [inference]

olefinic compound metabolic process [inference]

retinol metabolic process

carbohydrate derivative metabolic process [inference]

glycosyl compound metabolic process [inference]

glycoside metabolic process [inference]

aminoglycoside antibiotic metabolic process [inference]

daunorubicin metabolic process

doxorubicin metabolic process

organic cyclic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

lactone metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic cyclic compound biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic cyclic compound biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

hexitol metabolic process [inference]

sorbitol metabolic process [inference]

sorbitol biosynthetic process

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

primary alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

tertiary alcohol metabolic process [inference]

doxorubicin metabolic process

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

stress-activated protein kinase signaling cascade

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

unsaturated fatty acid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

cellular ketone metabolic process [inference]

quinone metabolic process [inference]

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

unsaturated fatty acid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

retinol metabolic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

lactone metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular developmental process [inference]

cell maturation [inference]

epithelial cell maturation

cellular response to stimulus [inference]

cellular response to stress [inference]

stress-activated protein kinase signaling cascade

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

cellular response to organic substance [inference]

cellular response to methylglyoxal

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to aldehyde [inference]

cellular response to methylglyoxal

cellular response to ketone [inference]

cellular response to methylglyoxal

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

multicellular organismal process [inference]

system process [inference]

renal system process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level water homeostasis [inference]

renal water homeostasis

developmental process [inference]

developmental maturation [inference]

anatomical structure maturation [inference]

cell maturation [inference]

epithelial cell maturation

anatomical structure development [inference]

tube development [inference]

collecting duct development [inference]

cellular developmental process [inference]

cell maturation [inference]

epithelial cell maturation

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level water homeostasis [inference]

renal water homeostasis

chemical homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level water homeostasis [inference]

renal water homeostasis

response to stimulus [inference]

response to stress [inference]

response to osmotic stress [inference]

hyperosmotic response [inference]

hyperosmotic salinity response [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

response to salt stress [inference]

hyperosmotic salinity response [inference]

cellular hyperosmotic salinity response

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

response to oxidative stress [inference]

response to reactive oxygen species [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

response to hydrogen peroxide [inference]

cellular response to hydrogen peroxide

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to stress [inference]

stress-activated protein kinase signaling cascade

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

response to abiotic stimulus [inference]

response to osmotic stress [inference]

hyperosmotic response [inference]

hyperosmotic salinity response [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

response to salt stress [inference]

hyperosmotic salinity response [inference]

cellular hyperosmotic salinity response

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

cellular response to abiotic stimulus [inference]

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

response to chemical [inference]

response to organic substance [inference]

response to hydrogen peroxide [inference]

cellular response to hydrogen peroxide

cellular response to organic substance [inference]

cellular response to methylglyoxal

cellular response to aldehyde [inference]

cellular response to methylglyoxal

response to ketone [inference]

response to methylglyoxal [inference]

cellular response to methylglyoxal

cellular response to ketone [inference]

cellular response to methylglyoxal

response to inorganic substance [inference]

response to hydrogen peroxide [inference]

cellular response to hydrogen peroxide

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

cellular response to organic substance [inference]

cellular response to methylglyoxal

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to aldehyde [inference]

cellular response to methylglyoxal

cellular response to ketone [inference]

cellular response to methylglyoxal

response to oxygen-containing compound [inference]

response to reactive oxygen species [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

response to hydrogen peroxide [inference]

cellular response to hydrogen peroxide

response to ketone [inference]

response to methylglyoxal [inference]

cellular response to methylglyoxal

cellular response to ketone [inference]

cellular response to methylglyoxal

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to aldehyde [inference]

cellular response to methylglyoxal

cellular response to ketone [inference]

cellular response to methylglyoxal

cellular response to stimulus [inference]

cellular response to stress [inference]

stress-activated protein kinase signaling cascade

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

cellular response to organic substance [inference]

cellular response to methylglyoxal

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to aldehyde [inference]

cellular response to methylglyoxal

cellular response to ketone [inference]

cellular response to methylglyoxal

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of smooth muscle cell proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

stress-activated protein kinase signaling cascade

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of smooth muscle cell proliferation

regulation of smooth muscle cell proliferation [inference]

positive regulation of smooth muscle cell proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of smooth muscle cell proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

retinol metabolic process

regulation of body fluid levels [inference]

regulation of urine volume

multicellular organismal-level water homeostasis [inference]

renal water homeostasis

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GO Term	Evidence Code	PMID
extracellular space	ISO
nucleoplasm	ISO
nucleoplasm	IEA
cytosol	ISO
cytosol	IDA	29238976

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm [inference]

cytoplasmic region [inference]

plasma membrane bounded cell projection cytoplasm

cytosol

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

paranodal junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

glial cell projection [inference]

Schwann cell microvillus

actin-based cell projection [inference]

microvillus [inference]

Schwann cell microvillus

Schmidt-Lanterman incisure

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome [inference]

mast cell granule

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome [inference]

mast cell granule

perinuclear region of cytoplasm

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GO Term	Evidence Code	PMID
retinal dehydrogenase activity	ISS
retinal dehydrogenase activity	ISO
alditol:NADP+ 1-oxidoreductase activity	ISO
alditol:NADP+ 1-oxidoreductase activity	IDA	7851421
alditol:NADP+ 1-oxidoreductase activity	IMP	17727625

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

aldo-keto reductase (NADP) activity [inference]

alcohol dehydrogenase (NADP+) activity [inference]

glycerol dehydrogenase [NAD(P)+] activity [inference]

glycerol dehydrogenase [NADP+] activity

oxidoreductase activity, acting on the CH-CH group of donors [inference]

oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [inference]

cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity

oxidoreductase activity, acting on the aldehyde or oxo group of donors [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [inference]

retinal dehydrogenase activity

glyceraldehyde oxidoreductase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

aldo-keto

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 2** entries
Gene Ontology
alditol
oxidoreductase activity

Displaying **all 4** entries
InterPro
Aldo-keto reductase
Aldo/keto reductase, conserved site
NADP-dependent oxidoreductase domain superfamily
NADP-dependent oxidoreductase domain

Ortholog

Displaying entries **11 - 20** of 83 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	57016	Xenbase:XB-GENE-5821742
Saccharomyces cerevisiae S288C	58810	SGD:S000002776
Saccharomyces cerevisiae S288C	78959	SGD:S000002776
Bos taurus	317748		BOVIN28458
Sus scrofa	396816		PIGXX12526
Canis lupus familiaris	607537		CANLF03714
Macaca mulatta	705957		MACMU32890
Pan troglodytes	737737		PANTR41456
Danio rerio	851974	ZFIN:ZDB-GENE-040625-7
Caenorhabditis elegans	852446	WB:WBGene00012723

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements