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solute carrier family 7 (cationic amino acid transporter, y+ system), member 3

Summary

Gene Symbol

Slc7a3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

11989

PubChem

11989

Alliance of Genome Resources

MGI:1100521

Annotation

Keyword

Amino-acid transport
Cell membrane
Glycoprotein
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P70423	Cationic amino acid transporter y+ Solute carrier family 7 member 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
L-arginine transmembrane transport	IDA ISO	9334265
lysine transport	ISO
L-ornithine import across plasma membrane	IEA ISO
L-ornithine transmembrane transport	IBA
L-arginine import across plasma membrane	IBA IEA ISO

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport

L-lysine import across plasma membrane

L-arginine transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

localization [inference]

establishment of localization [inference]

transport [inference]

transmembrane transport [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport

L-lysine import across plasma membrane

L-arginine transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport

L-lysine import across plasma membrane

L-arginine transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

basic amino acid transport [inference]

lysine transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport [inference]

L-lysine transport [inference]

lysine transport

L-lysine transmembrane transport

L-lysine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport

L-lysine import across plasma membrane

L-arginine transmembrane transport

ornithine transport

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport

L-lysine import across plasma membrane

L-arginine transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport

L-lysine import across plasma membrane

L-arginine transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

basic amino acid transport [inference]

lysine transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport [inference]

L-lysine transport [inference]

lysine transport

L-lysine transmembrane transport

L-lysine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport

L-lysine import across plasma membrane

L-arginine transmembrane transport

ornithine transport

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport

L-lysine import across plasma membrane

L-arginine transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport

L-lysine import across plasma membrane

L-arginine transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

modified amino acid transport [inference]

nitrogen compound transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport

L-lysine import across plasma membrane

L-arginine transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

basic amino acid transport [inference]

lysine transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport [inference]

L-lysine transport [inference]

lysine transport

L-lysine transmembrane transport

L-lysine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport

L-lysine import across plasma membrane

L-arginine transmembrane transport

ornithine transport

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

modified amino acid transport [inference]

import into cell [inference]

amino acid import across plasma membrane [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of TOR signaling

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of TOR signaling

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of TOR signaling

Displaying 1 entry
GO Term	Evidence Code	PMID
plasma membrane	IBA IEA ISO ISS	9334265

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
L-arginine transmembrane transporter activity	IBA IDA ISO	9334265
L-lysine transmembrane transporter activity	IBA IDA ISO	9334265
basic amino acid transmembrane transporter activity	IDA ISO	9334265
L-ornithine transmembrane transporter activity	IBA IEA ISO

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

basic amino acid transmembrane transporter activity

L-amino acid transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

basic amino acid transmembrane transporter activity

L-amino acid transmembrane transporter activity [inference]

modified amino acid transmembrane transporter activity [inference]

L-arginine transmembrane transporter activity

salt transmembrane transporter activity [inference]

L-lysine transmembrane transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

cationic amino acid transporter 3

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
P: Inorganic ion transport and metabolism

Displaying 1 entry
Gene Ontology
L-ornithine transmembrane transporter activity

Displaying **all 3** entries
InterPro
Amino acid/polyamine transporter I
Cationic amino acid transport permease
Cationic amino acid transporter, C-terminal

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0080208	metabolic dysfunction-associated steatotic liver disease	Alliance of Genome Resources
DOID:0111666	proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome	Alliance of Genome Resources
DOID:9455	lipid storage disease	Alliance of Genome Resources

Ortholog

Displaying entries **41 - 50** of **126** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Ictidomys tridecemlineatus	101963874	43179_0:000236	ICTTR07286
Chinchilla lanigera	102026632	34839_0:00354b	CHILA17536
Macaca fascicularis	102141440		MACFA44527
Capra hircus	102172339		CAPHI30661
Latimeria chalumnae	102354327		LATCH12839
Myotis lucifugus	102433520		MYOLU01249
Peromyscus maniculatus bairdii	102912259	230844_0:0052f9
Astyanax mexicanus	103021899		ASTMX11819
Astyanax mexicanus	103034170		ASTMX09327
Callorhinchus milii	103190480		CALMI43788