Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
Resources Genes Glycoproteins Lectins Glycolipids Glycans Pathways Diseases Organisms
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Other Information
Release Statistics Download
Tools
SugarDrawer GlycanBuilder Glycan Converters GlycoMaple GlycomeAtlas LM-GlycomeAtlas GALAXY MCAW GlycoSim GRable
Search Tools
Cross Search Glycan Search Publication Search Programmatic Access
Standards Ontologies Notations
LARGE xylosyl- and glucuronyltransferase 2

Summary
Gene Symbol
  • LARGE2
Aliases
  • FLJ35207
  • PP5656
Organism
Homo sapiens (human)
External Links
NCBI Gene
120071
GGDB ID
HGNC
16522
mRNA
map
  • 11p11.2
Protein
OMIM
KEGG Gene ID
hsa:120071
PubChem
120071
Alliance of Genome Resources
Annotation
Keyword
  • Glycoprotein
  • Glycosyltransferase
  • Golgi apparatus
  • Manganese
  • Metal-binding
  • Multifunctional enzyme
  • Proteomics identification
  • Reference proteome
  • Signal
  • Signal-anchor
  • Transferase
  • Transmembrane helix
Proteins
Displaying all 3 entries
UniProt Protein Name
Q8N3Y3
  • Glycosyltransferase-like 1B
  • LARGE xylosyl- and glucuronyltransferase 2
E9PIZ2
B3KP69
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 3 entries
GO Term Evidence Code PMID
muscle cell cellular homeostasis
protein O-linked glycosylation
protein O-linked mannosylation
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
GlycoGene Database (GGDB)
GGDB ID
gg172
Gene Symbol
  • LARGE2
Reactions
Displaying all 2 entries
Donor Acceptor Product Reference
UDP-GlcA
G16579HJ
UDP-Xyl
G16579HJ
Displaying all 2 entries
Donor Acceptor Product Reference
UDP-Xyl
G16579HJ
UDP-GlcA
G16579HJ
Orthologous Gene
Displaying all 2 entries
Species Protein mRNA
Rattus norvegicus NP_954538 NM_199107
Mus musculus NP_766258 NM_172670
KEGG BRITE Database
Orthology
K09668
Name
glycosyltransferase-like protein LARGE [EC:2.4.2.- 2.4.1.-]
References
Disease
Disease Ontology
Displaying entries 11 - 20 of 51 in total
DO ID Disease Name Source
DOID:0110278 autosomal recessive limb-girdle muscular dystrophy type 2D
DOID:0110279 autosomal recessive limb-girdle muscular dystrophy type 2E
DOID:0110280 autosomal recessive limb-girdle muscular dystrophy type 2F
DOID:0110281 autosomal recessive limb-girdle muscular dystrophy type 2G
DOID:0110282 autosomal recessive limb-girdle muscular dystrophy type 2H
DOID:0110283 autosomal recessive limb-girdle muscular dystrophy type 2J
DOID:0110284 autosomal recessive limb-girdle muscular dystrophy type 2L
DOID:0110285 autosomal recessive limb-girdle muscular dystrophy type 2Q
DOID:0110286 obsolete autosomal recessive limb-girdle muscular dystrophy type 2R
DOID:0110287 autosomal recessive limb-girdle muscular dystrophy type 2S
Ortholog
Displaying entries 1 - 10 of 46 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
187206 WB:WBGene00010716
446214 ZFIN:ZDB-GENE-050419-253
398936 Xenbase:XB-GENE-5872007
734944 Xenbase:XB-GENE-6256639
100125087 Xenbase:XB-GENE-5871953
100414072 CALJA03721
105592790 CERAT37864
102144935 MACFA09112
105471652 MACNE14400
101010541 PAPAN05200
About Release Notes Help Feedback
International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International

GlyCosmos Portal v4.0.0

Last updated: August 19, 2024