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6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

Summary

Gene Symbol

PFKFB3

Organism

Passer montanus (Eurasian tree sparrow)

External Links

NCBI Gene: 120512490
KEGG Gene ID: pmoa:120512490
PubChem: 120512490

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
fructose metabolic process	IEA	22301074
fructose 2,6-bisphosphate metabolic process	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

fructose 2,6-bisphosphate metabolic process

organophosphate metabolic process [inference]

fructose 2,6-bisphosphate metabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fructose metabolic process

organophosphate metabolic process [inference]

fructose 2,6-bisphosphate metabolic process

carbohydrate derivative metabolic process [inference]

fructose 2,6-bisphosphate metabolic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

fructose 2,6-bisphosphate metabolic process

organophosphate metabolic process [inference]

fructose 2,6-bisphosphate metabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying **all 3** entries
GO Term	Evidence Code	PMID
6-phosphofructo-2-kinase activity	IEA	22301074 30032202
fructose-2,6-bisphosphate 2-phosphatase activity	IEA	30032202
ATP binding	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

carbohydrate kinase activity [inference]

phosphofructokinase activity [inference]

6-phosphofructo-2-kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

phosphofructokinase activity [inference]

6-phosphofructo-2-kinase activity

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

carbohydrate phosphatase activity [inference]

sugar-phosphatase activity [inference]

fructose-2,6-bisphosphate 2-phosphatase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

6-phosphofructo-2-kinase/fructose-2

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis

Displaying **all 7** entries
Gene Ontology
6-phosphofructo-2-kinase activity
ATP binding
carbohydrate phosphorylation
catalytic activity
fructose 2,6-bisphosphate metabolic process
fructose metabolic process
nucleotide binding

Displaying **all 6** entries
InterPro
6-phosphofructo-2-kinase
Fructose-2,6-bisphosphatase
Histidine phosphatase superfamily, clade-1
Histidine phosphatase superfamily
P-loop containing nucleoside triphosphate hydrolase
Phosphoglycerate/bisphosphoglycerate mutase, active site

KEGG BRITE Database

Orthology

K01103

Name

6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 3 [EC:2.7.1.105 3.1.3.46]

References

9202288

Ortholog

Displaying entries **41 - 44** of 44 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Poecile atricapillus	131591608	48891_0:003c41
Poecile atricapillus	131593022	48891_0:0043eb
Ammospiza nelsoni	132073083	2857394_0:001374
Haemorhous mexicanus	132327884	30427_0:00161b

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024