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squalene epoxidase

Summary

Gene Symbol

SQLE

Organism

Hirundo rustica (Barn swallow)

External Links

NCBI Gene: 120751751
KEGG Gene ID: hrt:120751751
PubChem: 120751751

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cholesterol metabolic process	IEA	30032202
sterol biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

sterol metabolic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

sterol metabolic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

sterol metabolic process [inference]

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

sterol metabolic process [inference]

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	IEA	22301074
endoplasmic reticulum	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 2** entries
GO Term	Evidence Code	PMID
squalene monooxygenase activity	IEA	22301074 30032202
flavin adenine dinucleotide binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

monooxygenase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [inference]

squalene monooxygenase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [inference]

squalene monooxygenase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding

ion binding [inference]

anion binding [inference]

flavin adenine dinucleotide binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Passeriformes

Group Name

squalene monooxygenase

Functional Category

C: Energy production and conversion
H: Coenzyme transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 8** entries
Gene Ontology
cholesterol metabolic process
ergosterol biosynthetic process
flavin adenine dinucleotide binding
monooxygenase activity
oxidoreductase activity
squalene monooxygenase activity
sterol biosynthetic process
sterol metabolic process

Displaying **all 3** entries
InterPro
FAD/NAD(P)-binding domain superfamily
Squalene epoxidase
Squalene monooxygenase

KEGG BRITE Database

Orthology

K00511

Name

squalene monooxygenase [EC:1.14.14.17]

References

17852349

Ortholog

Displaying entries **1 - 10** of 44 in total

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Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Taeniopygia guttata	100225604	59729_0:0008bc
Ficedula albicollis	101806873	59894_0:000a59
Geospiza fortis	102033103	48883_0:00100d
Zonotrichia albicollis	102074085	44394_0:00010c
Pseudopodoces humilis	102109574	181119_0:0003b3
Corvus brachyrhynchos	103623503	85066_0:003871
Manacus vitellinus	103767413	328815_0:0009ae
Acanthisitta chloris	103797105	57068_0:000c98
Acanthisitta chloris	103807324	57068_0:003002
Serinus canaria	103814522	9135_0:000b31

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024