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catechol-O-methyltransferase

Summary

Gene Symbol

COMT

Organism

Bufo bufo (common toad)

External Links

NCBI Gene: 120988685
KEGG Gene ID: bbuf:120988685
PubChem: 120988685

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
catecholamine catabolic process	IEA	30032202
dopamine metabolic process	IEA	30032202
developmental process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

organic hydroxy compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organic substance metabolic process [inference]

organic cyclic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organic cyclic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

organic hydroxy compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organic hydroxy compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organic hydroxy compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

developmental process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane	IEA	30032202
dendrite	IEA	30032202
axon	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
catechol O-methyltransferase activity	IEA	22301074 30032202
magnesium ion binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity [inference]

O-methyltransferase activity [inference]

catechol O-methyltransferase activity

S-adenosylmethionine-dependent methyltransferase activity [inference]

catechol O-methyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Tetrapoda

Group Name

catechol o-methyltransferase

Functional Category

G: Carbohydrate transport and metabolism
H: Coenzyme transport and metabolism
J: Translation, ribosomal structure and biogenesis

Displaying entry **11 - 11** of 11 in total

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Gene Ontology
transferase activity

Displaying **all 3** entries
InterPro
Catechol O-methyltransferase, eukaryotic
Class I-like SAM-dependent O-methyltransferase
S-adenosyl-L-methionine-dependent methyltransferase superfamily

KEGG BRITE Database

Orthology

K00545

Name

catechol O-methyltransferase [EC:2.1.1.6]

References

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Bufo gargarizans	122924472	30331_0:00090c
Varanus komodoensis	123028549	61221_0:00289f
Mauremys mutica	123350960	74926_0:0049ca
Lemur catta	123626262	9447_0:004799
Perognathus longimembris pacificus	125349396	214514_0:000f42
Myodes glareolus	125411886	447135_0:002ab4
Sphaerodactylus townsendi	125442532	933632_0:003a2b
Suncus etruscus	125995103	109475_0:004475
Gymnogyps californianus	127022753	33616_0:002838
Acomys russatus	127193346	60746_0:001700

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024