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chondroitin sulfate proteoglycan 4

Summary

Gene Symbol

Cspg4

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

121021

PubChem

121021

Alliance of Genome Resources

MGI:2153093

Annotation

Keyword

Alternative splicing
Angiogenesis
Cell membrane
Cell projection
Developmental protein
Differentiation
Disulfide bond
Glycoprotein
Phosphoprotein
Proteoglycan
Reference proteome
Repeat
Signal
Tissue remodeling
Transducer
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8VHY0	Chondroitin sulfate proteoglycan NG2 Proteoglycan AN2
Q3URZ9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
angiogenesis	IEA
substrate-dependent cell migration	IGI	26437238
glial cell migration	IDA	10366628
negative regulation of neuron projection development	ISO
neuron remodeling	ISO

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

platelet-derived growth factor receptor signaling pathway

intracellular signal transduction

cellular developmental process [inference]

cell maturation [inference]

neuron maturation [inference]

neuron remodeling

cell motility [inference]

cell migration [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

ruffle assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

ruffle assembly

plasma membrane bounded cell projection organization [inference]

ruffle organization [inference]

ruffle assembly

plasma membrane bounded cell projection assembly [inference]

ruffle assembly

multicellular organismal process [inference]

tissue remodeling

developmental process [inference]

developmental maturation [inference]

anatomical structure maturation [inference]

cell maturation [inference]

neuron maturation [inference]

neuron remodeling

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

cellular developmental process [inference]

cell maturation [inference]

neuron maturation [inference]

neuron remodeling

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

platelet-derived growth factor receptor signaling pathway

intracellular signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

negative regulation of neuron projection development

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
ruffle	IDA	26437238
nucleoplasm	ISO
nucleoplasm	IEA
plasma membrane	ISO
plasma membrane	IDA	11668599

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

plasma membrane region [inference]

apical plasma membrane

cell projection membrane [inference]

lamellipodium membrane

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix

leading edge membrane [inference]

lamellipodium membrane

cell projection

plasma membrane bounded cell projection [inference]

ruffle

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	12458226 26437238
collagen binding	ISO
coreceptor activity	IDA	26437238
protein kinase binding	ISO
protein kinase binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

protein-containing complex binding [inference]

collagen binding

molecular transducer activity [inference]

signaling receptor activity [inference]

coreceptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Chondroitin sulfate proteoglycan 4

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying 1 entry
Gene Ontology
anatomical structure morphogenesis

Displaying **all 3** entries
InterPro
CSPG repeat
Concanavalin A-like lectin/glucanase domain superfamily
Laminin G domain

Ortholog

Displaying entries **1 - 10** of 94 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	1464	ZFIN:ZDB-GENE-050519-1	HUMAN24374
Rattus norvegicus	81651	ZFIN:ZDB-GENE-050519-1	RATNO41881
Danio rerio	121021	ZFIN:ZDB-GENE-050519-1
Canis lupus familiaris	487658		CANLF12720
Bos taurus	533653		BOVIN16617
Danio rerio	560393		DANRE26756
Macaca mulatta	713086		MACMU42207
Sus scrofa	733676		PIGXX32011
Pan troglodytes	737574		PANTR10856
Equus caballus	100061543		HORSE17116

GlyTouCan

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UniCarb-DR

LM-GlycoRepo

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OrthoDB (Group)

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Acknowledgements