GlyCosmos Portal

Submissions

clathrin heavy chain

Summary

Gene Symbol

CLTC

Organism

Homo sapiens (human)

External Links

NCBI Gene

1213

PubChem

1213

Alliance of Genome Resources

HGNC:2092

JoGo

CLTC

TogoVar

CLTC

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Autophagy
Coated pit
Cytoplasmic vesicle
Cytoskeleton
Direct protein sequencing
Disease variant
Intellectual disability
Mitosis
Phosphoprotein
Proteomics identification
Reference proteome
Repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q00610	Clathrin heavy chain on chromosome 17
A0A087WVQ6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 20 in total

1

2

3

4

Next ›

Last »
GO Term	Evidence Code	PMID
mitotic cell cycle	IMP	15858577
mitotic cell cycle	IBA
osteoblast differentiation	HDA	16210410
intracellular protein transport	NAS	1765375
receptor-mediated endocytosis	IMP	15858577

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

autophagy

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy

cellular process [inference]

cell cycle [inference]

mitotic cell cycle

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

endosomal transport [inference]

retrograde transport, endosome to Golgi

transcytosis [inference]

amyloid-beta clearance by transcytosis

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy

cellular developmental process [inference]

cell differentiation [inference]

osteoblast differentiation

cell division

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

retrograde transport, endosome to Golgi

cytosolic transport [inference]

retrograde transport, endosome to Golgi

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

process utilizing autophagic mechanism [inference]

autophagy

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component disassembly [inference]

protein-containing complex disassembly [inference]

protein depolymerization [inference]

vesicle uncoating [inference]

clathrin coat disassembly

cellular component assembly [inference]

protein-containing complex assembly [inference]

clathrin coat assembly

protein-containing complex organization [inference]

protein-containing complex disassembly [inference]

protein depolymerization [inference]

vesicle uncoating [inference]

clathrin coat disassembly

protein-containing complex assembly [inference]

clathrin coat assembly

multicellular organismal process [inference]

transcytosis [inference]

amyloid-beta clearance by transcytosis

amyloid-beta clearance [inference]

amyloid-beta clearance by transcytosis

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

osteoblast differentiation

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

iron ion transport [inference]

transferrin transport

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

endosomal transport [inference]

retrograde transport, endosome to Golgi

transcytosis [inference]

amyloid-beta clearance by transcytosis

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

retrograde transport, endosome to Golgi

cytosolic transport [inference]

retrograde transport, endosome to Golgi

organic substance transport [inference]

protein transport [inference]

nitrogen compound transport [inference]

protein transport [inference]

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis

establishment of protein localization [inference]

protein transport [inference]

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

retrograde transport, endosome to Golgi

cytosolic transport [inference]

retrograde transport, endosome to Golgi

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

retrograde transport, endosome to Golgi

cytosolic transport [inference]

retrograde transport, endosome to Golgi

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

regulation of polysaccharide biosynthetic process [inference]

regulation of hyaluronan biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

regulation of carbohydrate biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of hyaluronan biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

negative regulation of carbohydrate metabolic process [inference]

negative regulation of hyaluronan biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of hyaluronan biosynthetic process

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

regulation of polysaccharide biosynthetic process [inference]

regulation of hyaluronan biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of hyaluronan biosynthetic process

regulation of hyaluronan biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

regulation of polysaccharide biosynthetic process [inference]

regulation of hyaluronan biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

regulation of polysaccharide metabolic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of hyaluronan biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of polysaccharide metabolic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of hyaluronan biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

regulation of carbohydrate biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of hyaluronan biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

negative regulation of carbohydrate metabolic process [inference]

negative regulation of hyaluronan biosynthetic process

regulation of localization [inference]

regulation of cellular localization [inference]

regulation of protein localization [inference]

negative regulation of protein localization [inference]

negative regulation of protein localization to cell periphery [inference]

negative regulation of protein localization to plasma membrane

negative regulation of protein localization to membrane [inference]

negative regulation of protein localization to plasma membrane

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane [inference]

negative regulation of protein localization to plasma membrane

negative regulation of protein localization to cell periphery [inference]

negative regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

negative regulation of protein localization to plasma membrane

negative regulation of protein localization to membrane [inference]

negative regulation of protein localization to plasma membrane

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

negative regulation of carbohydrate metabolic process [inference]

negative regulation of hyaluronan biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of hyaluronan biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

negative regulation of protein localization [inference]

negative regulation of protein localization to cell periphery [inference]

negative regulation of protein localization to plasma membrane

negative regulation of protein localization to membrane [inference]

negative regulation of protein localization to plasma membrane

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

regulation of polysaccharide biosynthetic process [inference]

regulation of hyaluronan biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

regulation of microtubule-based process [inference]

regulation of microtubule cytoskeleton organization [inference]

regulation of spindle organization [inference]

regulation of mitotic spindle organization

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of hyaluronan biosynthetic process

negative regulation of protein localization [inference]

negative regulation of protein localization to cell periphery [inference]

negative regulation of protein localization to plasma membrane

negative regulation of protein localization to membrane [inference]

negative regulation of protein localization to plasma membrane

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

regulation of cytoskeleton organization [inference]

regulation of microtubule cytoskeleton organization [inference]

regulation of spindle organization [inference]

regulation of mitotic spindle organization

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of spindle organization [inference]

regulation of mitotic spindle organization

regulation of cellular localization [inference]

regulation of protein localization [inference]

negative regulation of protein localization [inference]

negative regulation of protein localization to cell periphery [inference]

negative regulation of protein localization to plasma membrane

negative regulation of protein localization to membrane [inference]

negative regulation of protein localization to plasma membrane

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane [inference]

negative regulation of protein localization to plasma membrane

negative regulation of protein localization to cell periphery [inference]

negative regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

negative regulation of protein localization to plasma membrane

negative regulation of protein localization to membrane [inference]

negative regulation of protein localization to plasma membrane

Displaying entries **1 - 5** of 29 in total

1

2

3

4

5

6

Next ›

Last »
GO Term	Evidence Code	PMID
lysosome	IDA
endosome	IDA
spindle	IDA	15858577
spindle	IBA
cytosol	TAS

GO Hierarchy

cellular component

protein-containing complex

membrane protein complex [inference]

membrane coat [inference]

clathrin coat

clathrin vesicle coat [inference]

clathrin coat of trans-Golgi network vesicle

clathrin coat of coated pit

vesicle coat [inference]

clathrin vesicle coat [inference]

clathrin coat of trans-Golgi network vesicle

clathrin complex

plasma membrane protein complex [inference]

clathrin coat of coated pit

cellular anatomical entity [inference]

cytosol

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

endolysosome membrane

coated vesicle membrane [inference]

clathrin-coated vesicle membrane [inference]

clathrin-coated endocytic vesicle membrane

endocytic vesicle membrane [inference]

clathrin-coated endocytic vesicle membrane

trans-Golgi network membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane [inference]

endolysosome membrane

endosome membrane [inference]

endolysosome membrane

coated vesicle membrane [inference]

clathrin-coated vesicle membrane [inference]

clathrin-coated endocytic vesicle membrane

endocytic vesicle membrane [inference]

clathrin-coated endocytic vesicle membrane

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

centriolar satellite

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

coated vesicle [inference]

clathrin-coated vesicle

clathrin-coated endocytic vesicle

endocytic vesicle [inference]

clathrin-coated endocytic vesicle

pigment granule [inference]

melanosome

extracellular vesicle

extracellular exosome

intracellular membrane-bounded organelle

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

coated vesicle [inference]

clathrin-coated vesicle

clathrin-coated endocytic vesicle

endocytic vesicle [inference]

clathrin-coated endocytic vesicle

pigment granule [inference]

melanosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle

extracellular exosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

spindle

mitotic spindle

intracellular organelle [inference]

intracellular membrane-bounded organelle

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

coated vesicle [inference]

clathrin-coated vesicle

clathrin-coated endocytic vesicle

endocytic vesicle [inference]

clathrin-coated endocytic vesicle

pigment granule [inference]

melanosome

intracellular non-membrane-bounded organelle [inference]

spindle

mitotic spindle

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle

extracellular exosome

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule [inference]

spindle microtubule [inference]

mitotic spindle microtubule

Displaying entries **6 - 10** of 10 in total

« First

‹ Prev

1

2
GO Term	Evidence Code	PMID
clathrin light chain binding	IBA
clathrin light chain binding	IPI	4066749
low-density lipoprotein particle receptor binding	IPI	26005850
disordered domain specific binding	IPI	11756460
ubiquitin-specific protease binding	IPI	26756164