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MIRAGE
bone morphogenetic protein 2
Summary
- Gene Symbol
-
- Bmp2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Chondrogenesis
- Cleavage on pair of basic residues
- Cytokine
- Developmental protein
- Differentiation
- Disulfide bond
- Glycoprotein
- Growth factor
- Osteogenesis
- Phosphoprotein
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P21274 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II | ||
| negative regulation of transcription by RNA polymerase II | ||
| negative regulation of transcription by RNA polymerase II | ||
| osteoblast differentiation | ||
| osteoblast differentiation |
GO Hierarchy
- positive regulation of cartilage development
- positive regulation of cartilage development
biological process
metabolic process [inference]
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of hormone biosynthetic process [inference]
regulation of lipid biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of hormone biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of hormone metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of protein metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of lipid metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
positive regulation of signal transduction [inference]
negative regulation of signal transduction [inference]
regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]
regulation of intracellular signal transduction [inference]
positive regulation of signaling [inference]
negative regulation of signaling [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cell differentiation [inference]
positive regulation of response to stimulus [inference]
positive regulation of developmental process [inference]
positive regulation of cell differentiation [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of signaling [inference]
negative regulation of cellular process [inference]
negative regulation of response to stimulus [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
positive regulation of signal transduction [inference]
negative regulation of signal transduction [inference]
regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]
regulation of intracellular signal transduction [inference]
positive regulation of response to stimulus [inference]
negative regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cell differentiation [inference]
positive regulation of developmental process [inference]
positive regulation of cell differentiation [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of signal transduction [inference]
negative regulation of signal transduction [inference]
regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]
regulation of intracellular signal transduction [inference]
positive regulation of cell communication [inference]
negative regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of hormone biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cell differentiation [inference]
negative regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
regulation of biological quality [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| extracellular space | ||
| extracellular space | ||
| nucleus |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytokine activity | ||
| cytokine activity | ||
| cytokine activity | ||
| cytokine activity | ||
| protein binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Bone morphogenetic protein 2
- Functional Category
-
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cytokine activity |
| growth factor activity |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 650 | Xenbase:XB-GENE-481829 | HUMAN56055 | |
| 652 | FB:FBgn0000490 | ||
| 654 | WB:WBGene00000936 | ||
| 655 | WB:WBGene00000936 | ||
| 12156 | Xenbase:XB-GENE-481829 | ||
| 12159 | FB:FBgn0000490 | ||
| 12160 | WB:WBGene00000936 | ||
| 12161 | WB:WBGene00000936 | ||
| 12162 | WB:WBGene00000936 | ||
| 12164 | WB:WBGene00000936 |
