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MIRAGE
phospholipase C epsilon 1

Summary
Gene Symbol
  • PLCE1
Organism
Varanus komodoensis (Komodo dragon)
NCBI Gene
123018488
KEGG Gene ID
vko:123018488
PubChem
123018488
Gene Ontology (GO)
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
Functional Category
  • F: Nucleotide transport and metabolism
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Displaying all 6 entries
Gene Ontology
hydrolase activity
lipid metabolic process
phosphatidylinositol phospholipase C activity
phosphatidylinositol-mediated signaling
release of sequestered calcium ion into cytosol
small GTPase-mediated signal transduction
Displaying entries 1 - 10 of 16 in total
InterPro
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1, EF-hand domain
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1, RA domain 2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1, catalytic domain
C2 domain superfamily
C2 domain
EF-hand domain pair
PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
Phosphatidylinositol-specific phospholipase C, X domain
Phosphoinositide phospholipase C family
Phosphoinositide-specific phospholipase C, EF-hand-like domain
KEGG BRITE Database
Orthology
K05860
Name
phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
References
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026