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calcium/calmodulin-dependent protein kinase II, beta

Summary

Gene Symbol

Camk2b

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

12323

PubChem

12323

Alliance of Genome Resources

MGI:88257

Annotation

Keyword

ATP-binding
Calmodulin-binding
Cytoskeleton
Differentiation
Direct protein sequencing
Membrane
Neurogenesis
Phosphoprotein
Proteomics identification
Reference proteome
Sarcoplasmic reticulum
Serine/threonine-protein kinase
Synapse
Transmembrane helix

Proteins

Displaying **all 5** entries
UniProt	Protein Name
Q5SVI2
Q8BL41
Q5SVJ0
Q68EG2
P28652

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 30 in total

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GO Term	Evidence Code	PMID
G1/S transition of mitotic cell cycle	IMP	12660151
inhibitory G protein-coupled receptor phosphorylation	IDA	19332541
protein phosphorylation
calcium ion transport	IMP	12660151
nervous system development	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

cellular process [inference]

signal transduction [inference]

apoptotic signaling pathway

cell cycle process [inference]

cell cycle phase transition [inference]

mitotic cell cycle phase transition [inference]

G1/S transition of mitotic cell cycle

cell cycle G1/S phase transition [inference]

G1/S transition of mitotic cell cycle

mitotic cell cycle process [inference]

mitotic cell cycle phase transition [inference]

G1/S transition of mitotic cell cycle

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cellular developmental process [inference]

cell differentiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

cell projection morphogenesis

reproductive process [inference]

activation of meiosis involved in egg activation

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

neuromuscular process [inference]

neuromuscular process controlling balance

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis

anatomical structure development [inference]

system development [inference]

nervous system development

cellular developmental process [inference]

cell differentiation

response to stimulus [inference]

response to chemical [inference]

response to inorganic substance [inference]

response to metal ion [inference]

response to cadmium ion

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport

organic substance transport [inference]

calcium ion transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, cholinergic

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity

regulation of long-term neuronal synaptic plasticity

long-term synaptic potentiation

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of localization [inference]

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of neuron migration

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of cell cycle [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of cell cycle process [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of dendritic spine morphogenesis

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of synapse maturation

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of dendritic spine development [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of synapse maturation

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of reproductive process [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of dendrite morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of dendritic spine morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of dendrite development [inference]

regulation of dendrite morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of dendritic spine development [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of synapse maturation

regulation of dendritic spine development [inference]

positive regulation of dendritic spine development [inference]

positive regulation of dendritic spine morphogenesis

regulation of synapse maturation

positive regulation of synapse maturation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of cellular process [inference]

signal transduction [inference]

apoptotic signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, cholinergic

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity

regulation of long-term neuronal synaptic plasticity

long-term synaptic potentiation

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of cell cycle [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of cell cycle process [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of dendritic spine morphogenesis

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of synapse maturation

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of dendritic spine morphogenesis

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development

positive regulation of dendritic spine morphogenesis

regulation of dendrite development [inference]

regulation of dendrite morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of dendritic spine morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

regulation of nuclear division [inference]

regulation of meiotic nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

regulation of synapse organization [inference]

regulation of synapse maturation

positive regulation of synapse maturation

regulation of postsynapse organization [inference]

regulation of dendritic spine morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of dendritic spine morphogenesis

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of synapse maturation

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of meiotic nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of cell cycle process [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of cell cycle [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of cell cycle process [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

regulation of meiotic cell cycle [inference]

regulation of meiotic nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of neuron migration

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of reproductive process [inference]

regulation of meiotic cell cycle [inference]

regulation of meiotic nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

positive regulation of reproductive process [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

activation of meiosis [inference]

activation of meiosis involved in egg activation

regulation of biological quality [inference]

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity

regulation of long-term neuronal synaptic plasticity

long-term synaptic potentiation

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GO Term	Evidence Code	PMID
cytoplasm	IBA
centrosome	IEA
cytosol	IDA	9882483
calcium- and calmodulin-dependent protein kinase complex	ISO
postsynaptic density	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

calcium- and calmodulin-dependent protein kinase complex

catalytic complex [inference]

calcium- and calmodulin-dependent protein kinase complex

cellular anatomical entity [inference]

cytoplasm

microtubule organizing center [inference]

centrosome

cytosol

membrane

organelle membrane [inference]

endoplasmic reticulum membrane [inference]

sarcoplasmic reticulum membrane

bounding membrane of organelle [inference]

sarcoplasmic reticulum membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

dendrite

perikaryon

organelle [inference]

postsynaptic specialization [inference]

postsynaptic density

spindle midzone

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GO Term	Evidence Code	PMID
calcium-dependent protein serine/threonine kinase activity	ISO
protein kinase binding	ISO
identical protein binding	ISO
protein homodimerization activity	ISO
phospholipase binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

calcium-dependent protein kinase activity [inference]

calcium-dependent protein serine/threonine kinase activity

protein serine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

calcium-dependent protein kinase activity [inference]

calcium-dependent protein serine/threonine kinase activity

protein serine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

calcium-dependent protein kinase activity [inference]

calcium-dependent protein serine/threonine kinase activity

protein serine kinase activity

structural molecule activity [inference]

structural constituent of cytoskeleton [inference]

structural constituent of postsynaptic actin cytoskeleton

structural constituent of synapse [inference]

structural constituent of postsynapse [inference]

structural constituent of postsynaptic actin cytoskeleton

binding [inference]

protein binding

calmodulin binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

phospholipase binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **21 - 30** of 49 in total

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Species	Gene ID	Orthologous MAtrix
Cavia porcellus	100717077	CAVPO18908
Sarcophilus harrisii	100918427	SARHA02005
Otolemur garnettii	100955681	OTOGA05489
Pan paniscus	100986246	PANPA36217
Papio anubis	101008925	PAPAN30470
Saimiri boliviensis boliviensis	101052251	SAIBB18030
Felis catus	101098615	FELCA05318
Gorilla gorilla gorilla	101148194	GORGO39439
Jaculus jaculus	101604525	JACJA04098
Heterocephalus glaber	101718749	HETGA08822

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Acknowledgements