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sphingosine kinase 2

Summary

Gene Symbol

SPHK2

Organism

Ursus americanus (American black bear)

External Links

NCBI Gene: 123776264
KEGG Gene ID: uar:123776264
PubChem: 123776264

Annotation

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
sphingosine biosynthetic process	IEA	30032202
sphinganine-1-phosphate biosynthetic process	IEA	30032202
positive regulation of apoptotic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

sphingosine biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

sphinganine-1-phosphate metabolic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingoid metabolic process [inference]

sphingosine metabolic process [inference]

sphingosine biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

sphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

sphinganine-1-phosphate metabolic process [inference]

sphinganine-1-phosphate biosynthetic process

phospholipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

sphinganine-1-phosphate metabolic process [inference]

sphinganine-1-phosphate biosynthetic process

phospholipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

sphingosine biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

sphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphinganine-1-phosphate metabolic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingoid metabolic process [inference]

sphingosine metabolic process [inference]

sphingosine biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

phospholipid metabolic process [inference]

sphinganine-1-phosphate metabolic process [inference]

sphinganine-1-phosphate biosynthetic process

phospholipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphinganine-1-phosphate metabolic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingoid metabolic process [inference]

sphingosine metabolic process [inference]

sphingosine biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

phospholipid metabolic process [inference]

sphinganine-1-phosphate metabolic process [inference]

sphinganine-1-phosphate biosynthetic process

phospholipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

diol metabolic process [inference]

sphingosine metabolic process [inference]

sphingosine biosynthetic process

diol biosynthetic process [inference]

sphingosine biosynthetic process

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphinganine-1-phosphate metabolic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingoid metabolic process [inference]

sphingosine metabolic process [inference]

sphingosine biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

phospholipid metabolic process [inference]

sphinganine-1-phosphate metabolic process [inference]

sphinganine-1-phosphate biosynthetic process

phospholipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

sphinganine-1-phosphate metabolic process [inference]

sphinganine-1-phosphate biosynthetic process

phospholipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

sphinganine-1-phosphate metabolic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingoid metabolic process [inference]

sphingosine metabolic process [inference]

sphingosine biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

diol metabolic process [inference]

sphingosine metabolic process [inference]

sphingosine biosynthetic process

diol biosynthetic process [inference]

sphingosine biosynthetic process

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

diol biosynthetic process [inference]

sphingosine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

sphinganine-1-phosphate metabolic process [inference]

sphinganine-1-phosphate biosynthetic process

phospholipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

sphinganine-1-phosphate metabolic process [inference]

sphinganine-1-phosphate biosynthetic process

phospholipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

sphingosine biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

sphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphinganine-1-phosphate metabolic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

sphingoid metabolic process [inference]

sphingosine metabolic process [inference]

sphingosine biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

sphingoid biosynthetic process [inference]

sphingosine biosynthetic process

phospholipid metabolic process [inference]

sphinganine-1-phosphate metabolic process [inference]

sphinganine-1-phosphate biosynthetic process

phospholipid biosynthetic process [inference]

sphinganine-1-phosphate biosynthetic process

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

regulation of cellular process [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
intracellular membrane-bounded organelle	IEA	30032202
cytoplasm	IEA	30032202
membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

Displaying 1 entry
GO Term	Evidence Code	PMID
D-erythro-sphingosine kinase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

lipid kinase activity [inference]

D-erythro-sphingosine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

D-erythro-sphingosine kinase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K04718

Name

sphingosine kinase [EC:2.7.1.91]

References

Ortholog

Displaying entries **11 - 20** of 61 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Cercocebus atys	105595245		CERAT28494
Macaca mulatta	718088		MACMU18024
Macaca nemestrina	105478648		MACNE39731
Mandrillus leucophaeus	105539178		MANLE32656
Gorilla gorilla gorilla	129528634		GORGO16971
Pan paniscus	100992056		PANPA20946
Homo sapiens	56848		HUMAN44839
Vulpes vulpes	112931373		VULVU26894
Ailuropoda melanoleuca	100479407		AILME14193
Mustela putorius furo	101672769		MUSPF06934

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Last updated: August 19, 2024