GlyCosmos Portal

GlyTouCan

Glycan Structure Repository

GlyComb

Glycoconjugate Repository

GlycoPOST

Glycomics MS raw data Repository

UniCarb-DR

Glycomics MS Repository for glycan annotations from GlycoWorkbench

LM-GlycoRepo

Repository for lectin-assisted multimodality data

All Resources

Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms

Other Information

Release Statistics Download

Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

SPNS lysolipid transporter 2, sphingosine-1-phosphate

Summary

Gene Symbol

SPNS2

Organism

Homo sapiens (human)

External Links

NCBI Gene

124976

PubChem

124976

Alliance of Genome Resources

HGNC:26992

Annotation

Keyword

3D-structure
Cell membrane
Disease variant
Endosome
Lipid transport
Non-syndromic deafness
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8IVW8	Protein spinster homolog 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **11 - 13** of 13 in total

« First

‹ Prev

1

2

3
GO Term	Evidence Code	PMID
regulation of humoral immune response	ISS
bone development	IEA
sphingosine-1-phosphate receptor signaling pathway	IBA ISS

GO Hierarchy

biological process

immune system process [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

leukocyte migration [inference]

mononuclear cell migration [inference]

lymphocyte migration

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

sphingosine-1-phosphate receptor signaling pathway

sphingolipid mediated signaling pathway [inference]

sphingosine-1-phosphate receptor signaling pathway

cellular metabolic process [inference]

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

mononuclear cell migration [inference]

lymphocyte migration

transmembrane transport

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

hematopoietic or lymphoid organ development [inference]

lymph node development

bone development

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

localization [inference]

establishment of localization [inference]

transport [inference]

transmembrane transport

organic substance transport [inference]

lipid transport

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of leukocyte migration [inference]

regulation of mononuclear cell migration [inference]

regulation of lymphocyte migration [inference]

regulation of T cell migration

regulation of immune response [inference]

regulation of humoral immune response

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

regulation of mononuclear cell migration [inference]

regulation of lymphocyte migration [inference]

regulation of T cell migration

regulation of response to stimulus [inference]

regulation of immune response [inference]

regulation of humoral immune response

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

sphingosine-1-phosphate receptor signaling pathway

sphingolipid mediated signaling pathway [inference]

sphingosine-1-phosphate receptor signaling pathway

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

regulation of mononuclear cell migration [inference]

regulation of lymphocyte migration [inference]

regulation of T cell migration

regulation of pigmentation [inference]

regulation of developmental pigmentation [inference]

regulation of eye pigmentation

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane	IBA
plasma membrane	TAS
endosome membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

endosome membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
sphingolipid transporter activity	IBA IDA TAS	21084291
transmembrane transporter activity	IBA IEA

GO Hierarchy

molecular function

transporter activity [inference]

lipid transporter activity [inference]

sphingolipid transporter activity

transmembrane transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

transporter

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
MFS transporter superfamily
Major facilitator superfamily domain
Major facilitator superfamily

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0111643	autosomal recessive nonsyndromic deafness 115	Alliance of Genome Resources
DOID:14503	neuronal ceroid lipofuscinosis	Alliance of Genome Resources
DOID:1927	sphingolipidosis	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 72 in total

« First

‹ Prev

1

2

3

4

5

6

…

Next ›

Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Taeniopygia guttata	100223347			TAEGU07884
Rattus norvegicus	100270678		RGD:2303312
Callithrix jacchus	100388936			CALJA36149
Sus scrofa	100523398			PIGXX03163
Oreochromis niloticus	100707944			ORENI04510
Cavia porcellus	100729353			CAVPO13969
Otolemur garnettii	100941705			OTOGA04174
Pan paniscus	100986286	9597_0:0047d9
Papio anubis	101012930			PAPAN13994
Gorilla gorilla gorilla	101128340	9595_0:00482a

About Release Notes Help Feedback

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

GlyCosmos Portal v4.1.0

Last updated: December 9, 2024