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cadherin 6

Summary

Gene Symbol

Cdh6

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

12563

PubChem

12563

Alliance of Genome Resources

MGI:107435

Annotation

Keyword

3D-structure
Calcium
Cell adhesion
Cell membrane
Cleavage on pair of basic residues
Glycoprotein
Membrane
Metal-binding
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P97326	Kidney cadherin
Q3UYK5

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
cell morphogenesis	IBA
cell-cell junction assembly	IBA
homophilic cell adhesion via plasma membrane adhesion molecules	IEA
Notch signaling pathway	IDA	23117660
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IBA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion mediated by cadherin

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

cell motility [inference]

cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell-cell junction assembly

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly

cell-cell junction organization [inference]

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

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GO Term	Evidence Code	PMID
nucleoplasm	ISO
nucleoplasm	IEA
plasma membrane	ISO
plasma membrane	IDA	12139922
adherens junction	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

catenin complex

cellular anatomical entity [inference]

nucleoplasm

membrane [inference]

plasma membrane

cell junction

synapse

glutamatergic synapse

anchoring junction [inference]

cell-cell junction [inference]

adherens junction

Displaying **all 3** entries
GO Term	Evidence Code	PMID
calcium ion binding	IEA
beta-catenin binding	IBA
cadherin binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

beta-catenin binding

cell adhesion molecule binding [inference]

cadherin binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Cadherin

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 7** entries
Gene Ontology
adherens junction organization
cadherin binding
calcium ion binding
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
cell-cell adhesion mediated by cadherin
cell-cell junction assembly
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 6** entries
InterPro
Cadherin conserved site
Cadherin, Y-type LIR-motif
Cadherin-like superfamily
Cadherin-like
Cadherin
Catenin binding domain superfamily

Ortholog

Displaying entries **1 - 10** of 72 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	1004	Xenbase:XB-GENE-484592	HUMAN78710
Danio rerio	1007	ZFIN:ZDB-GENE-050320-92
Xenopus tropicalis	12563	Xenbase:XB-GENE-484592
Rattus norvegicus	25409	Xenbase:XB-GENE-484592	RATNO24520
Pan troglodytes	461937		PANTR35791
Bos taurus	537946		BOVIN16112
Macaca mulatta	695557		MACMU38689
Monodelphis domestica	100016010		MONDO18466
Equus caballus	100068795		HORSE20482
Ornithorhynchus anatinus	100078953		ORNAN30862