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cyclic nucleotide gated channel subunit beta 1

Summary

Gene Symbol

CNGB1

Organism

Homo sapiens (human)

External Links

NCBI Gene

1258

PubChem

1258

Alliance of Genome Resources

HGNC:2151

JoGo

CNGB1

TogoVar

CNGB1

Annotation

Keyword

3D-structure
Alternative splicing
Calcium channel
Cell membrane
Cell projection
Disease variant
Ligand-gated ion channel
Olfaction
Proteomics identification
Reference proteome
Retinitis pigmentosa
Sodium channel
Transmembrane helix
Vision
cAMP-binding
cGMP-binding

Proteins

Displaying 1 entry
UniProt	Protein Name
Q14028	Cyclic nucleotide-gated cation channel 4 Cyclic nucleotide-gated cation channel gamma Cyclic nucleotide-gated cation channel modulatory subunit Glutamic acid-rich protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	PMID
retina homeostasis	IMP	15557452
retina homeostasis	IBA
monoatomic cation transport	IDA	24164424
potassium ion transport	ISS
sodium ion transport	ISS

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

ion channel modulating, G protein-coupled receptor signaling pathway

phototransduction

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

photoreceptor cell outer segment organization

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of chemical stimulus [inference]

sensory perception of smell

sensory perception of light stimulus [inference]

visual perception

photoreceptor cell maintenance

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

retina homeostasis

developmental process [inference]

developmental maturation [inference]

anatomical structure maturation [inference]

nerve maturation [inference]

cranial nerve maturation [inference]

olfactory nerve maturation

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

retina homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

inorganic ion homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus [inference]

phototransduction

detection of visible light [inference]

detection of light stimulus involved in visual perception

detection of light stimulus involved in sensory perception [inference]

detection of light stimulus involved in visual perception

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

detection of light stimulus [inference]

phototransduction

detection of visible light [inference]

detection of light stimulus involved in visual perception

detection of light stimulus involved in sensory perception [inference]

detection of light stimulus involved in visual perception

detection of abiotic stimulus [inference]

detection of light stimulus [inference]

phototransduction

detection of visible light [inference]

detection of light stimulus involved in visual perception

detection of light stimulus involved in sensory perception [inference]

detection of light stimulus involved in visual perception

response to chemical [inference]

response to odorant

detection of stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus [inference]

phototransduction

detection of visible light [inference]

detection of light stimulus involved in visual perception

detection of light stimulus involved in sensory perception [inference]

detection of light stimulus involved in visual perception

detection of abiotic stimulus [inference]

detection of light stimulus [inference]

phototransduction

detection of visible light [inference]

detection of light stimulus involved in visual perception

detection of light stimulus involved in sensory perception [inference]

detection of light stimulus involved in visual perception

detection of chemical stimulus [inference]

detection of chemical stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception of smell

detection of stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception of smell

detection of light stimulus involved in sensory perception [inference]

detection of light stimulus involved in visual perception

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport

metal ion transport [inference]

potassium ion transport

sodium ion transport

sodium ion transmembrane transport

calcium ion transport

calcium ion transmembrane transport

monoatomic cation transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

organic substance transport [inference]

calcium ion transport

calcium ion transmembrane transport

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

ion channel modulating, G protein-coupled receptor signaling pathway

phototransduction

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of biological quality [inference]

regulation of membrane potential [inference]

membrane depolarization

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
photoreceptor outer segment	IBA
plasma membrane	TAS
plasma membrane	IBA
intracellular cyclic nucleotide activated cation channel complex	IBA
Golgi-associated vesicle membrane	TAS

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex

monoatomic ion channel complex [inference]

cation channel complex [inference]

intracellular cyclic nucleotide activated cation channel complex

transporter complex [inference]

transmembrane transporter complex

monoatomic ion channel complex [inference]

cation channel complex [inference]

intracellular cyclic nucleotide activated cation channel complex

cellular anatomical entity [inference]

photoreceptor outer segment

rod photoreceptor outer segment

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

Golgi-associated vesicle membrane

bounding membrane of organelle [inference]

Golgi-associated vesicle membrane

ciliary membrane

non-motile cilium membrane

plasma membrane region [inference]

cell projection membrane [inference]

ciliary membrane

non-motile cilium membrane

presynapse [inference]

terminal bouton

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
intracellular cAMP-activated cation channel activity	IDA	34699778
intracellular cAMP-activated cation channel activity	IBA
intracellular cGMP-activated cation channel activity	IDA	24164424 34699778
intracellular cGMP-activated cation channel activity	IBA
calcium channel activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

ligand-gated monoatomic ion channel activity

intracellular ligand-gated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

cyclic nucleotide-activated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity

calcium ion transmembrane transporter activity [inference]

calcium channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity

calcium ion transmembrane transporter activity [inference]

calcium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

ligand-gated monoatomic ion channel activity

intracellular ligand-gated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

cyclic nucleotide-activated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity

intracellular ligand-gated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

cyclic nucleotide-activated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity [inference]

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity

calcium ion transmembrane transporter activity [inference]

calcium channel activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

cGMP binding

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

guanyl ribonucleotide binding [inference]

cGMP binding

cyclic nucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

guanyl ribonucleotide binding [inference]

cGMP binding

ion binding [inference]

anion binding [inference]

protein-containing complex binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

cGMP binding

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

guanyl ribonucleotide binding [inference]

cGMP binding

cyclic nucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

guanyl ribonucleotide binding [inference]

cGMP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

guanyl ribonucleotide binding [inference]

cGMP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Cyclic nucleotide-gated cation channel

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
cGMP binding
intracellular cAMP-activated cation channel activity
intracellular cGMP-activated cation channel activity
monoatomic ion channel activity
monoatomic ion transport

Displaying **all 4** entries
InterPro
Cyclic nucleotide-binding domain superfamily
Cyclic nucleotide-binding domain
Cyclic nucleotide-binding, conserved site
RmlC-like jelly roll fold

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0110402	retinitis pigmentosa 45	Alliance of Genome Resources
DOID:10584	retinitis pigmentosa	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements