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phospholipase A2 group XIIA

Summary

Gene Symbol

PLA2G12A

Organism

Panthera uncia (snow leopard)

External Links

NCBI Gene: 125923014
KEGG Gene ID: puc:125923014
PubChem: 125923014

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
proteolysis	IEA	22301074 30032202
arachidonic acid secretion	IEA	22301074
apoptotic process	IEA	30032202
lipid catabolic process	IEA	22301074 30032202
phospholipid metabolic process	IEA	22301074

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

catabolic process [inference]

organic substance catabolic process [inference]

lipid catabolic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process

protein metabolic process [inference]

proteolysis

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

organic substance catabolic process [inference]

lipid catabolic process

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process

localization [inference]

establishment of localization [inference]

transport [inference]

secretion [inference]

icosanoid secretion [inference]

arachidonic acid secretion

organic substance transport [inference]

lipid transport [inference]

fatty acid transport [inference]

long-chain fatty acid transport [inference]

arachidonate transport [inference]

arachidonic acid secretion

organic anion transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

fatty acid transport [inference]

long-chain fatty acid transport [inference]

arachidonate transport [inference]

arachidonic acid secretion

icosanoid transport [inference]

icosanoid secretion [inference]

arachidonic acid secretion

arachidonate transport [inference]

arachidonic acid secretion

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

fatty acid transport [inference]

long-chain fatty acid transport [inference]

arachidonate transport [inference]

arachidonic acid secretion

icosanoid transport [inference]

icosanoid secretion [inference]

arachidonic acid secretion

arachidonate transport [inference]

arachidonic acid secretion

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region	IEA	22301074 30032202
cytoplasm	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
phospholipase A2 activity	IEA	22301074 30032202
cysteine-type endopeptidase activity involved in execution phase of apoptosis	IEA	30032202
calcium ion binding	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

cysteine-type endopeptidase activity [inference]

cysteine-type endopeptidase activity involved in apoptotic process [inference]

cysteine-type endopeptidase activity involved in execution phase of apoptosis

cysteine-type peptidase activity [inference]

cysteine-type endopeptidase activity [inference]

cysteine-type endopeptidase activity involved in apoptotic process [inference]

cysteine-type endopeptidase activity involved in execution phase of apoptosis

hydrolase activity, acting on ester bonds [inference]

lipase activity [inference]

phospholipase activity [inference]

phospholipase A2 activity

carboxylic ester hydrolase activity [inference]

phospholipase A2 activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

cysteine-type endopeptidase activity [inference]

cysteine-type endopeptidase activity involved in apoptotic process [inference]

cysteine-type endopeptidase activity involved in execution phase of apoptosis

cysteine-type peptidase activity [inference]

cysteine-type endopeptidase activity [inference]

cysteine-type endopeptidase activity involved in apoptotic process [inference]

cysteine-type endopeptidase activity involved in execution phase of apoptosis

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Carnivora

Group Name

caspase-6

Functional Category

C: Energy production and conversion
I: Lipid transport and metabolism
L: Replication, recombination and repair

Displaying **all 5** entries
Gene Ontology
cysteine-type endopeptidase activity involved in apoptotic process
cysteine-type endopeptidase activity
hydrolase activity
positive regulation of neuron apoptotic process
proteolysis

Displaying **all 7** entries
InterPro
Caspase-like domain superfamily
Peptidase C14, caspase domain
Peptidase C14, caspase non-catalytic subunit p10
Peptidase C14, p20 domain
Peptidase C14A, caspase catalytic domain
Peptidase family C14A, His active site
Peptidase family C14A, cysteine active site

KEGG BRITE Database

Orthology

K04396

Name

caspase 6 [EC:3.4.22.59]

References

7796396

Ortholog

Displaying entries **41 - 46** of 46 in total

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Species	Gene ID	OrthoDB
Lutra lutra	125093276	9657_0:000a6c
Prionailurus viverrinus	125163574	61388_0:001120
Nyctereutes procyonoides	129521236	34880_0:00346a
Neofelis nebulosa	131507199	61452_0:000f93
Mustela lutreola	131829380	9666_0:000792
Mustela nigripes	132002150	77151_0:0007d5