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carboxyl ester lipase

Summary

Gene Symbol

Cel

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

12613

PubChem

12613

Alliance of Genome Resources

MGI:88374

Annotation

Keyword

Disulfide bond
Glycoprotein
Hydrolase
Lipid degradation
Reference proteome
Repeat
Secreted
Serine esterase
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3V2H7
Q64285	Bile salt-stimulated lipase Carboxyl ester lipase Cholesterol esterase Pancreatic lysophospholipase Sterol esterase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
pancreatic juice secretion	IBA IEA ISO
intestinal cholesterol absorption	IEA ISO
ceramide catabolic process	IBA IMP	11733511

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

ceramide metabolic process [inference]

ceramide catabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide catabolic process

sphingolipid catabolic process [inference]

ceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

ceramide catabolic process

catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

ceramide catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

ceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

ceramide catabolic process

cellular metabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

ceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide catabolic process

sphingolipid catabolic process [inference]

ceramide catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

ceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

ceramide catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

ceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide catabolic process

sphingolipid catabolic process [inference]

ceramide catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

ceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

ceramide catabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

ceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide catabolic process

sphingolipid catabolic process [inference]

ceramide catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

ceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

ceramide catabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide catabolic process

sphingolipid catabolic process [inference]

ceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

ceramide catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

ceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

ceramide catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

ceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide catabolic process

sphingolipid catabolic process [inference]

ceramide catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

ceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process [inference]

ceramide catabolic process

multicellular organismal process [inference]

system process [inference]

digestive system process [inference]

pancreatic juice secretion

intestinal absorption [inference]

intestinal lipid absorption [inference]

intestinal cholesterol absorption

secretion by tissue [inference]

pancreatic juice secretion

localization [inference]

establishment of localization [inference]

transport [inference]

secretion [inference]

body fluid secretion [inference]

pancreatic juice secretion

secretion by tissue [inference]

pancreatic juice secretion

intestinal absorption [inference]

intestinal lipid absorption [inference]

intestinal cholesterol absorption

organic substance transport [inference]

lipid transport [inference]

sterol transport [inference]

cholesterol transport [inference]

intestinal cholesterol absorption

intestinal lipid absorption [inference]

intestinal cholesterol absorption

organic hydroxy compound transport [inference]

sterol transport [inference]

cholesterol transport [inference]

intestinal cholesterol absorption

biological regulation [inference]

regulation of biological quality [inference]

regulation of body fluid levels [inference]

body fluid secretion [inference]

pancreatic juice secretion

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein-containing complex	ISO
zymogen granule	ISO
extracellular region	IEA
extracellular space	ISO
cytoplasm	ISO ISS

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

zymogen granule

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

zymogen granule

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

zymogen granule

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
retinyl-palmitate esterase activity	IBA ISO
sterol esterase activity	IBA IEA ISO
triglyceride lipase activity	IBA IEA ISO
protein-containing complex binding	ISO
glycosphingolipid binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

lipase activity [inference]

phospholipase activity [inference]

lysophospholipase activity

carboxylic ester hydrolase activity [inference]

short-chain carboxylesterase activity [inference]

acetylesterase activity

retinyl-palmitate esterase activity

binding [inference]

lipid binding [inference]

sphingolipid binding [inference]

glycosphingolipid binding

glycolipid binding [inference]

glycosphingolipid binding

protein-containing complex binding

carbohydrate derivative binding [inference]

glycolipid binding [inference]

glycosphingolipid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

bile salt-activated lipase

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
T: Signal transduction mechanisms

Displaying entries **1 - 10** of 11 in total

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Gene Ontology
ceramide catabolic process
chemical synaptic transmission
hydrolase activity
modulation of chemical synaptic transmission
neuron cell-cell adhesion
pancreatic juice secretion
postsynaptic membrane assembly
presynaptic membrane assembly
retinyl-palmitate esterase activity
sterol esterase activity

Displaying **all 4** entries
InterPro
Alpha/Beta hydrolase fold
Carboxylesterase type B, active site
Carboxylesterase type B, conserved site
Carboxylesterase, type B

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0111105	maturity-onset diabetes of the young type 8	Alliance of Genome Resources
DOID:3153	lipomatosis	Alliance of Genome Resources
DOID:9352	type 2 diabetes mellitus	Alliance of Genome Resources
DOID:9744	type 1 diabetes mellitus	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **130** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	1056		HGNC:1848	HUMAN99084
Rattus norvegicus	24254	10116_1:001490	RGD:2331	RATNO27675
Bos taurus	280748			BOVIN03367
Danio rerio	322481		ZFIN:ZDB-GENE-030131-1201	DANRE20821
Canis lupus familiaris	491280			CANLF19325
Danio rerio	565117			DANRE20771
Macaca mulatta	722291			MACMU12537
Oryctolagus cuniculus	100009339			RABIT18451
Monodelphis domestica	100017734			MONDO06893
Equus caballus	100066592			HORSE23786

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024