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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
complement component factor i
Summary
- Gene Symbol
-
- Cfi
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Calcium
- Cleavage on pair of basic residues
- Complement pathway
- Disulfide bond
- Glycoprotein
- Metal-binding
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| Q61129 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| innate immune response | ||
| complement activation, classical pathway | ||
| complement activation |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| metal ion binding | ||
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- DNA PRIMASE
- Functional Category
-
- K: Transcription
- L: Replication, recombination and repair
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| DNA replication, synthesis of RNA primer |
| metal ion binding |
| nucleotidyltransferase activity |
| transferase activity |
| InterPro |
|---|
| DNA primase, small subunit, eukaryotic/archaeal |
| DNA primase, small subunit |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050419 | complement factor I deficiency | |
| DOID:0080301 | atypical hemolytic-uremic syndrome | |
| DOID:0110025 | age related macular degeneration 13 | |
| DOID:10873 | Kuhnt-Junius degeneration | |
| DOID:1184 | nephrotic syndrome | |
| DOID:2921 | glomerulonephritis | |
| DOID:4448 | macular degeneration | |
| DOID:8893 | psoriasis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 3426 | HGNC:5394 | HUMAN76999 | ||
| 79126 | 10116_1:00107e | RGD:620429 | RATNO24437 | |
| 471271 | PANTR34318 | |||
| 478514 | CANLF13150 | |||
| 478515 | CANLF13150 | |||
| 513197 | BOVIN31070 | |||
| 557557 | ZFIN:ZDB-GENE-110922-7 | |||
| 613100 | Xenbase:XB-GENE-5953276 | |||
| 720962 | MACMU37286 | |||
| 100010034 | MONDO27981 |
