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cardiolipin synthase 1

Summary

Gene Symbol

CRLS1

Organism

Antechinus flavipes (yellow-footed antechinus)

External Links

NCBI Gene: 127548508
KEGG Gene ID: afz:127548508
PubChem: 127548508

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
cardiolipin biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	IEA	22301074
mitochondrion	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 2** entries
GO Term	Evidence Code	PMID
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity	IEA	22301074
cardiolipin synthase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

phosphotransferase activity, for other substituted phosphate groups [inference]

CDP-alcohol phosphatidyltransferase activity [inference]

CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity

phosphatidyltransferase activity [inference]

cardiolipin synthase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Metatheria

Group Name

cardiolipin synthase (CMP-forming)

Functional Category

H: Coenzyme transport and metabolism
I: Lipid transport and metabolism
J: Translation, ribosomal structure and biogenesis
M: Cell wall/membrane/envelope biogenesis

Displaying **all 6** entries
Gene Ontology
cardiolipin biosynthetic process
cardiolipin synthase (CMP-forming)
lipid metabolic process
phosphatidyltransferase activity
phospholipid biosynthetic process
phosphotransferase activity, for other substituted phosphate groups

Displaying **all 2** entries
InterPro
CDP-alcohol phosphatidyltransferase, transmembrane domain
CDP-alcohol phosphatidyltransferase

KEGG BRITE Database

Orthology

K08744

Name

cardiolipin synthase (CMP-forming) [EC:2.7.8.41]

References

Ortholog

Displaying **all 7** entries
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Monodelphis domestica	100033289	13616_0:000b3c
Sarcophilus harrisii	100915821	9305_0:001698
Phascolarctos cinereus	110207804	38626_0:0001a7
Vombatus ursinus	114026623	29139_0:004856
Trichosurus vulpecula	118843134	9337_0:001da9
Dromiciops gliroides	122743348	33562_0:001f57
Gracilinanus agilis	123234744	191870_0:001c87

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024